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颈椎延髓结合部“髓内神经鞘瘤”伪装成胶质瘤:手术中的意外。

Cervico Medullary Junction "Intramedullary Schwannoma" Masquerading As Glioma: A Surprise During Surgery.

机构信息

Department of Neurosurgery, KEM Hospital, Mumbai, Maharashtra, India; Advanced Endoscopic Skull Base And Lateral Skull Base, Italy.

Department of Neurosurgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

出版信息

Neurol India. 2021 Nov-Dec;69(6):1747-1752. doi: 10.4103/0028-3886.333465.

Abstract

BACKGROUND

Intramedullary schwannomas (IS) at cervicomedullary junction (CMJ) are exceedingly uncommon. There is hardly any clinicoradiological marker for preoperative diagnosis and prognostication.

CASE

We report a case of a 17-year-old boy with progressive spastic quadriparesis of six months duration. On radiology, there was a contrast-enhancing lesion expanding the cord extending from the medulla to C5 level. During surgery, the cord was expanded and the tumor was eccentric. Histopathology and immunohistochemistry were suggestive of schwannoma. In view of the ill-defined plane of separation from the normal neural tissue, only subtotal resection could be achieved.

CONCLUSION

Schwannoma should be considered as a remote differential of intramedullary lesions. The extent of resection should be tailored according to the plane of dissection and intraoperative neuromonitoring guidance. Though a masquerader, schwannoma carries better prognosis than rest of the pathologies.

摘要

背景

颈髓交界处的髓内神经鞘瘤(IS)极为罕见。术前诊断和预后几乎没有任何临床影像学标志物。

病例报告

我们报告了一例 17 岁男孩,表现为进行性痉挛性四肢瘫痪,病程为六个月。影像学检查显示有一个增强对比的病变,从延髓扩展到 C5 水平。在手术过程中,脊髓扩张,肿瘤偏心。组织病理学和免疫组织化学检查提示为神经鞘瘤。由于与正常神经组织的分离界限不明确,只能进行次全切除。

结论

神经鞘瘤应被视为髓内病变的一个鉴别诊断。切除范围应根据解剖平面和术中神经监测指导来调整。虽然神经鞘瘤是一种伪装者,但它的预后比其他病理类型要好。

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