Infertility Research Center, Department of Obstetrics and Gynecology, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
BMC Pregnancy Childbirth. 2022 Jan 3;22(1):2. doi: 10.1186/s12884-021-04299-y.
Ectopic pregnancy is one of the leading causes of pregnancy-related mortality; the treatment strategies associated with this condition entail complications, such as recurrence of ectopic pregnancy or infertility. The objective of this study was to evaluate the recurrence and fertility rate after salpingostomy in patients with tubal ectopic pregnancy.
This cross-sectional retrospective study was conducted at four referral centers of Obstetrics and Gynecology, under the supervision of Shiraz University of Medical Sciences (Iran). The medical records of 125 patients with tubal pregnancy were reviewed. These patients underwent laparoscopic salpingostomy from April 2009 to March 2016.Data on maternal age, BMI, history of previous EP, genital tract infection, IUD insertion, history of previous surgery, and infertility were further obtained. The patients were followed up for approximately 1 to 7 years. The recurrence of EP and subsequent pregnancy rate were assessed during the follow-up period.
There was no statistically significant relationship between post-salpingostomy recurrence and maternal age, previous abdominopelvic surgery, and history of infertility(P = .425); however, the post-salpingostomy recurrence of EP was correlated with BMI (P = 0.001), previous history of EP (P = 0.001), genital tract infection (P = 0.001), and IUD insertion (P = 003). Among 95 women who had no contraception, pregnancy occurred in 51 cases (53.6%) and recurrence of EP was observed in 16 patients (12.8%).
Our results suggest that salpingostomy is a safe method with a low risk of recurrence and good fertility outcomes for women who consider future pregnancy.
宫外孕是导致妊娠相关死亡的主要原因之一;与这种情况相关的治疗策略会带来一些并发症,例如宫外孕的再次发生或不孕。本研究旨在评估输卵管妊娠患者行输卵管切开术后的复发率和生育能力。
这是一项在 Shiraz 大学医学科学(伊朗)监督下在四个妇产科转诊中心进行的横断面回顾性研究。回顾了 125 例输卵管妊娠患者的病历。这些患者于 2009 年 4 月至 2016 年 3 月接受腹腔镜输卵管切开术。进一步获得了母亲年龄、BMI、既往 EP 病史、生殖道感染、宫内节育器放置史、既往手术史和不孕史等数据。患者随访时间约为 1 至 7 年。在随访期间评估 EP 的复发和随后的妊娠率。
输卵管切开术后 EP 的复发与母亲年龄、既往腹部盆腔手术和不孕史之间无统计学显著关系(P=0.425);然而,EP 输卵管切开术后的复发与 BMI(P=0.001)、既往 EP 病史(P=0.001)、生殖道感染(P=0.001)和宫内节育器放置史(P=0.003)有关。在 95 名没有避孕的女性中,有 51 例(53.6%)怀孕,16 例(12.8%)发生 EP 复发。
我们的结果表明,对于考虑未来妊娠的女性,输卵管切开术是一种安全的方法,复发风险低,生育结局良好。