两名重度成骨不全症和髋臼内陷患者的梗阻性便秘

Obstructive Constipation in Two Patients With Severe Osteogenesis Imperfecta and Acetabular Protrusio.

作者信息

Stockwell Erin, Wallace Maegen

机构信息

From the University of Nebraska Medical Center, Omaha, NE (Dr. Stockwell and Dr. Wallace) and the University of Nebraska Medical Center, Children's Hospital and Medical Center Omaha (Dr. Wallace).

Correspondence to Dr. Stockwell:

出版信息

J Am Acad Orthop Surg Glob Res Rev. 2022 Jan 4;6(1):e21.00194. doi: 10.5435/JAAOSGlobal-D-21-00194.

DOI:10.5435/JAAOSGlobal-D-21-00194

PMID:34982054

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8735770/

Abstract

Osteogenesis imperfecta (OI) is a rare genetic condition resulting in decreased bone density and bony deformity and a wide variety of extraskeletal manifestations. Acetabular protrusio and constipation are both commonly associated with OI. We present two cases of severe pelvic deformity resulting in mechanical colonic outlet obstruction, which were successfully treated with a colostomy. Colostomy as the definitive treatment of severe constipation in OI has not previously been reported in the literature.

摘要

成骨不全症（OI）是一种罕见的遗传性疾病，会导致骨密度降低和骨骼畸形以及多种骨骼外表现。髋臼内陷和便秘都与成骨不全症常见相关。我们报告了两例严重骨盆畸形导致机械性结肠出口梗阻的病例，通过结肠造口术成功治疗。结肠造口术作为成骨不全症严重便秘的最终治疗方法，此前文献中尚未有报道。