State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, China.
College of Mechanical Engineering, Tianjin University, Tianjin 300072, China.
Langmuir. 2022 Jan 18;38(2):856-862. doi: 10.1021/acs.langmuir.1c03066. Epub 2022 Jan 6.
Bacterial residue is one of the main causes of diseases and economic losses. In recent years, microfabrication technology has inspired the introduction of microstructures on the surfaces of relevant materials to provide antibacterial effects. This antibacterial method has become a popular research topic due to its safety, effectiveness, and stability. However, its exact mechanism is still under debate. In this study, normal force was introduced to bacteria on GaN nanopillars to investigate the mechanical sterilization effects and a computer simulation was conducted. The results show that the normal force induces highly efficient mechanical sterilization of the nanopillars, and their surfaces impede the attachment of bacteria. This study provides insights into the antibacterial effect of nanopillars and offers a potential antibacterial tool with high efficiency.
细菌残留是疾病和经济损失的主要原因之一。近年来,微纳制造技术启发人们在相关材料表面引入微结构以提供抗菌效果。由于其安全性、有效性和稳定性,这种抗菌方法已成为热门研究课题。然而,其确切机制仍存在争议。在这项研究中,我们向 GaN 纳米柱上的细菌引入法向力,以研究其力学杀菌效果并进行计算机模拟。结果表明,法向力可诱导纳米柱实现高效力学杀菌,其表面可阻碍细菌的附着。本研究为纳米柱的抗菌效果提供了新的见解,并为高效的潜在抗菌工具提供了新的思路。