Tuğba Ramaslı Gürsoy, Tuğba Şişmanlar Eyüboğlu, Ayşe Tana Aslan, Zeynep Reyhan Onay, Pelin Asfuroğlu, Cem Kaya, Ramazan Karabulut
Division of Pediatric Chest Diseases, Department of Pediatrics, Gazi University School of Medicine, Ankara, Turkey.
Department of Pediatric Surgery, Gazi University School of Medicine, Ankara, Turkey.
Turk Arch Pediatr. 2021 Jul 1;56(4):380-385. doi: 10.5152/TurkArchPediatr.2021.20125. eCollection 2021 Jul.
This study was aimed to investigate the complications arising during follow-up and the reasons for hospitalization in pediatric patients who were operated on for esophageal atresia (EA) and tracheoesophageal fistula (TEF).
Between 2007 and 2019, all patients operated for EA and TEF were evaluated in terms of age, gender, age at diagnosis, post-op, and complications in follow-up.
In the study, 28 of 50 patients were operated on for EA and TEF, 14 for isolated EA, and 8 for isolated TEF. The mean age of the patients was 4.9 ± 4.4 years, and 18 (36%) of them were female. The median age of diagnosis was 1 (IQR: 1-3) day and the mean follow-up duration was 4.6 ± 4.1 years. During follow-up, 84% of patients had recurrent pneumonia, 60% gastroesophageal reflux (GER), 34% growth retardation, 30% restrictive lung disease, and 18% scoliosis. Postoperative pneumonia, hospitalization, development of stricture and growth retardation were more frequent in patients with GER ( < .05). Patients with scoliosis had more frequent pneumonia and hospitalization rates ( < .05).
Hospital admissions of the patients with EA and TEF were higher due to GER, recurrent pneumonia, restrictive lung disease, and scoliosis in the follow-up. Pneumonia, hospitalization, stricture in the esophagus, and growth retardation were observed more frequently in patients with GER. Patients should be followed up by the pediatric pulmonology, gastroenterology, and orthopedic departments.
本研究旨在调查接受食管闭锁(EA)和气管食管瘘(TEF)手术的儿科患者在随访期间出现的并发症及住院原因。
2007年至2019年间,对所有接受EA和TEF手术的患者进行了年龄、性别、诊断年龄、术后情况及随访并发症方面的评估。
在该研究中,50例患者中28例接受了EA和TEF手术,14例接受了单纯EA手术,8例接受了单纯TEF手术。患者的平均年龄为4.9±4.4岁,其中18例(36%)为女性。诊断的中位年龄为1天(四分位间距:1 - 3天),平均随访时间为4.6±4.1年。随访期间,84%的患者出现反复肺炎,60%出现胃食管反流(GER),34%出现生长发育迟缓,30%出现限制性肺病,18%出现脊柱侧弯。GER患者术后肺炎、住院、狭窄形成及生长发育迟缓更为常见(P<0.05)。脊柱侧弯患者肺炎和住院率更高(P<0.05)。
EA和TEF患者在随访期间因GER、反复肺炎、限制性肺病和脊柱侧弯导致的住院率较高。GER患者肺炎、住院、食管狭窄及生长发育迟缓更为常见。患者应由儿科肺病科、胃肠病科和骨科进行随访。