Department 5 Internal Medicine, 4th Medical Clinic, Faculty of Medicine, "Iuliu Haţieganu" University of Medicine and Pharmacy, 400015 Cluj-Napoca, Romania.
Department 2 Functional Sciences, Discipline of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, "Iuliu Haţieganu" University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania.
Int J Environ Res Public Health. 2021 Dec 25;19(1):207. doi: 10.3390/ijerph19010207.
Cardiovascular diseases create an important burden on the public health systems, especially in the elderly, mostly because this group of patients frequently suffer from multiple comorbidities. Accumulating cardiovascular risk factors during their lifetime has a detrimental effect on an older adult's health status. The modifiable and non-modifiable cardiovascular risk factors are very diverse, and are frequently in a close relationship with the metabolic comorbidities of the elderly, mainly obesity and Diabetes Mellitus. In this review, we aim to present the most important cardiovascular risk factors which link aging and cardiovascular diseases, starting from the pathophysiological links between these factors and the aging process. Next, we will further review the main interconnections between obesity and Diabetes Mellitus and cardiovascular diseases of the elderly. Lastly, we consider the most important aspects related to prevention through lifestyle changes and physical activity on the occurrence of cardiovascular diseases in the elderly.
心血管疾病对公共卫生系统造成了重大负担，尤其是在老年人中，主要是因为这组患者经常患有多种合并症。一生中积累的心血管危险因素对老年人的健康状况有不利影响。可改变和不可改变的心血管危险因素非常多样化，并且经常与老年人的代谢合并症密切相关，主要是肥胖和糖尿病。在这篇综述中，我们旨在从这些因素与衰老过程之间的病理生理学联系出发，介绍与衰老和心血管疾病相关的最重要的心血管危险因素。接下来，我们将进一步探讨肥胖和糖尿病与老年人心血管疾病之间的主要相互关系。最后，我们考虑与老年人心血管疾病发生相关的最重要的方面，包括通过生活方式改变和体育活动进行预防。
