Bye M R, Bernstein L, Shah K, Ellaurie M, Rubinstein A
Division of Pediatric Pulmonary Medicine, Albert Einstein College of Medicine, Bronx, NY 10461.
Pediatr Pulmonol. 1987 Nov-Dec;3(6):425-8. doi: 10.1002/ppul.1950030609.
Between October, 1985 and May 1987, 29 children (mean age 22 +/- 22 months, range 2-54 months) with AIDS or ARC developed acute respiratory illness. The initial diagnostic procedure was flexible fiberoptic bronchoscopy, with bronchoalveolar lavage (BAL). BAL was positive for Pneumocystis carinii in 14 and for respiratory syncytial virus, Staphylococcus aureus, and Escherichia coli in 3 additional patients. Subsequent lung tissue analysis and/or clinical course suggested no false negative lavages. Complications possibly related to the procedure occurred in two patients. We find BAL an effective diagnostic technique in these patients, offering a less invasive alternative to open lung biopsy.
1985年10月至1987年5月期间，29名患有艾滋病或艾滋病相关综合征（ARC）的儿童（平均年龄22±22个月，范围为2 - 54个月）出现了急性呼吸道疾病。初始诊断程序为使用支气管肺泡灌洗（BAL）的可弯曲纤维支气管镜检查。14例患者的支气管肺泡灌洗结果显示卡氏肺孢子虫阳性，另有3例患者的灌洗结果显示呼吸道合胞病毒、金黄色葡萄球菌和大肠杆菌阳性。随后的肺组织分析和/或临床病程表明灌洗没有假阴性结果。两名患者出现了可能与该操作相关的并发症。我们发现支气管肺泡灌洗在这些患者中是一种有效的诊断技术，为开胸肺活检提供了一种侵入性较小的替代方法。
