两性离子盐的结构工程与优化，助力热敏材料的快速发现。

Structural Engineering and Optimization of Zwitterionic Salts for Expeditious Discovery of Thermoresponsive Materials.

机构信息

Department of Chemistry and Biochemistry, National Chung Cheng University, Chiayi 62102, Taiwan, China.

出版信息

Molecules. 2021 Dec 31;27(1):257. doi: 10.3390/molecules27010257.

DOI:10.3390/molecules27010257

PMID:35011489

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8746428/

Abstract

This work reported the discovery of -triflimide (NTf)-based zwitter-ionic liquids (ZILs) that exhibit UCST-type phase transitions in water, and their further structural optimization in fine-tuning polarity to ultimately afford newfangled thermosensitive materials carrying attractive and biocompatible values that clearly demonstrated the true value of the tunability of ZIL structure. This research established that with non-aromatic, acyclic ZILs as small-molecule thermoresponsive materials, their mixing and de-mixing with water triggered by temperatures are entirely reversible.

摘要

本工作报道了发现基于 -三氟甲磺酰亚胺（NTf）-的两性离子液体（ZILs）在水中表现出上临界溶解温度（UCST）型相转变，并对其进行了进一步的结构优化以精细调节极性，最终得到了具有吸引力和生物相容性的新型热敏材料，这充分展示了 ZIL 结构可调性的真正价值。该研究确立了以非芳香、无环 ZILs 作为小分子热响应材料，它们与水的混合和去混合由温度引发，完全是可逆的。