播散性咽峡炎链球菌侵袭性感染并形成颅内硬膜下脓肿

Disseminated Streptococcus anginosus invasive infection with intracranial subdural abscess formation.

作者信息

Suzuki Tetsuya, Morioka Shinichiro, Nomoto Hidetoshi, Takaya Saho, Ishikane Masahiro, Yanagisawa Shunsuke, Hayakawa Kayoko, Ohmagari Norio

机构信息

Department of Infectious Diseases, Disease Control and Prevention Center, National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.

出版信息

J Infect Chemother. 2022 May;28(5):696-698. doi: 10.1016/j.jiac.2021.12.016. Epub 2022 Jan 10.

DOI:10.1016/j.jiac.2021.12.016

PMID:35016822

Abstract

We report the case of a 67-year-old woman with disseminated Streptococcus anginosus invasive infection. Even under a maximal dose of susceptible antibiotics, her condition was complicated by pulmonary septic emboli and intracranial subdural abscess. Effective antibiotics and emergent surgical drainage were performed, but the sequelae of aphasia and hemiplegia remained. Underlying immunocompromised conditions of diabetes mellitus and monoclonal gammopathy of unknown significance might partially affect the clinical course of invasive S. anginosus infection. Once the infection becomes invasive, it can be refractory and difficult to treat. Clinicians should acknowledge the characteristics of invasive S. anginosus infection.

摘要

我们报告了一例67岁女性播散性咽峡炎链球菌侵袭性感染的病例。即使在使用最大剂量的敏感抗生素治疗下，她的病情仍因肺脓毒性栓子和颅内硬膜下脓肿而复杂化。虽进行了有效的抗生素治疗和紧急手术引流，但失语和偏瘫的后遗症仍然存在。潜在的免疫功能低下状况，如糖尿病和意义未明的单克隆丙种球蛋白病，可能部分影响侵袭性咽峡炎链球菌感染的临床病程。一旦感染变为侵袭性，它可能难以治愈且治疗困难。临床医生应认识到侵袭性咽峡炎链球菌感染的特点。