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老年患者阑尾切除术后并发症相关因素分析。

Factors associated with postoperative complications following appendectomy in elderly patients.

机构信息

Gulhane Training and Research Hospital, Department of General Surgery - Ankara, Turkey.

出版信息

Rev Assoc Med Bras (1992). 2021 Oct;67(10):1485-1490. doi: 10.1590/1806-9282.20210672.

Abstract

OBJECTIVE

Appendicitis in elderly patients is more challenging due to delayed presentation and higher comorbidities, which are associated with increased postoperative morbidity. The aim of this study was to evaluate factors that predict 30-day complications in elderly patients undergoing appendectomy.

METHODS

The records of elderly patients who underwent appendectomy were reviewed. The primary outcome was 30-day postoperative complications. Independent variables examined included demographic data, comorbidities, preoperative laboratory values, pathological findings, and surgical features. Both univariate and multivariate regression analyses were performed to identify factors associated with postoperative complications.

RESULTS

Evaluation was performed on 80 patients, comprising 63.8% females with a mean age of 71.3 years. Notably, 19 (23.8%) patients had one or more complications within 30 days after surgery. No significant difference was found between patients with and without complications in respect of age, gender, or laboratory features. The rates of American Society of Anesthesiologists scores 3-4 (p=0.006), hypertension (p=0.016), cardiovascular disease (p=0.049), and obesity (p=0.040) were significantly higher for patients with complications than for those without. On multivariate analysis, obesity (OR 9.41), chronic obstructive pulmonary disease (OR 9.72), and open appendectomy (OR 14.87) were independently associated with 30-day postoperative complications.

CONCLUSIONS

Older patients undergoing appendectomy tend to have poorer outcomes than younger patients. Therefore, it is critical to identify factors that could reduce the possibility of adverse outcomes in this frail population. The results of this study suggest that obesity, chronic obstructive pulmonary disease, and an open approach are independent factors for complications in elderly patients undergoing appendectomy.

摘要

目的

老年患者的阑尾炎更具挑战性,因为其表现延迟且合并症更多,这与术后发病率增加有关。本研究旨在评估预测老年阑尾炎患者术后 30 天并发症的相关因素。

方法

回顾性分析行阑尾切除术的老年患者的病历资料。主要结局为术后 30 天内的并发症。检查的独立变量包括人口统计学数据、合并症、术前实验室值、病理发现和手术特征。进行单变量和多变量回归分析以确定与术后并发症相关的因素。

结果

共评估了 80 例患者,其中 63.8%为女性,平均年龄为 71.3 岁。值得注意的是,19 例(23.8%)患者在术后 30 天内发生了 1 种或多种并发症。有并发症的患者和无并发症的患者在年龄、性别或实验室特征方面无显著差异。并发症患者的美国麻醉医师协会评分 3-4 分(p=0.006)、高血压(p=0.016)、心血管疾病(p=0.049)和肥胖(p=0.040)的发生率明显高于无并发症的患者。多变量分析显示,肥胖(OR 9.41)、慢性阻塞性肺疾病(OR 9.72)和开放性阑尾切除术(OR 14.87)与术后 30 天内的并发症独立相关。

结论

与年轻患者相比,老年患者行阑尾切除术的预后更差。因此,识别可能降低这一脆弱人群不良结局可能性的因素至关重要。本研究结果表明,肥胖、慢性阻塞性肺疾病和开放性手术是老年阑尾炎患者发生并发症的独立因素。

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