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活体供肾切除术后大量乳糜性腹水成功采用淋巴栓塞治疗。

Massive Chylous Ascites After Living Donor Nephrectomy Successfully Treated With Lymphatic Embolization.

机构信息

Augusta University Health, GA, USA.

出版信息

J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096211065631. doi: 10.1177/23247096211065631.

Abstract

Chylous ascites may result from a variety of pathological conditions, most of them from nontraumatic causes, such as congenital defects of the lymphatic system, infections, liver cirrhosis, and malignancy. Rarely, chylous ascites occurs as an iatrogenic complication after left-sided laparoscopic donor nephrectomy (LDN). Injury to the cisterna chyli and its main lymphatic tributaries around the para-aortic region intraoperatively can cause the lymphatic fluid to accumulate. There is currently no standardized treatment for chylous ascites as there have only been 54 cases documented to date. Most patients can be managed with conservative therapy. Recommended guidelines include high-protein and low-fat diet with medium-chain triglycerides. Paracentesis is often used as a diagnostic and therapeutic first-line measure with total parenteral nutrition (TPN), bowel rest, and somatostatin analogue as adjunct therapies. We present a case of massive chylous ascites refractory to conservative therapy. The patient had progressive abdominal distention and unintentional weight gain 2 weeks postoperatively warranting multiple paracenteses of >7 L of chylous fluid. Ultimately, the patient was successfully treated with lymphatic embolization using N-butyl cyanoacrylate glue.

摘要

乳糜性腹水可由多种病理情况引起,大多数是非创伤性原因,如淋巴系统先天性缺陷、感染、肝硬化和恶性肿瘤。罕见情况下,乳糜性腹水也可作为左侧腹腔镜供肾切除术(LDN)的医源性并发症发生。术中在主动脉旁区域损伤乳糜池及其主要淋巴支流可导致淋巴液积聚。目前尚无针对乳糜性腹水的标准化治疗方法,因为迄今为止仅记录了 54 例病例。大多数患者可以通过保守治疗进行管理。推荐的指南包括高蛋白、低脂饮食和中链甘油三酯。腹腔穿刺术常作为诊断和治疗的一线措施,同时辅以全肠外营养(TPN)、肠道休息和生长抑素类似物。我们报告了一例术后 2 周发生大量乳糜性腹水且对保守治疗无效的病例。患者出现进行性腹胀和非自愿性体重增加,需要多次抽取超过 7 L 的乳糜液。最终,患者成功接受了 N-丁基氰基丙烯酸酯胶的淋巴栓塞治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b345/8771747/2d137bbcec51/10.1177_23247096211065631-fig1.jpg

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