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[重症监护病房治疗的弥漫性腹膜炎术后腹腔灌洗]

[Postoperative peritoneal irrigation in generalized peritonitis treated in an intensive care unit].

作者信息

Manélli J C, Lallemand J, Kiégel P, Rouzaud M, Palayret D

出版信息

Ann Anesthesiol Fr. 1978;19(11-12):909-13.

PMID:35070
Abstract

Over a period of four years, 16 patients with generalized peritonitis have been treated by postoperative peritoneal irrigation in an Intensive Care Unit. The majority of cases involved postoperative peritonitis accompanied by severe visceral failure. The irrigation liquid, containing an antibacterial agent, was perfused for between one and eleven days at a high flow rate (mean 16.5 I). The overall mortality in the series was extremely high (75 p. 100), and even greater (85 p. 100) if only the cases of postoperative peritonitis were considered. Anatomical examination of the peritoneum, performed on reintervention or at autopsy, revealed an abnormally high incidence of residual abscesses. These are responsable for the continuation or recurrence of infection, and explain the high mortality. These observations, combined with the frequent occurrence of local or general complications, led the authors to reject peritoneal irrigation in postoperative peritonitis in the presence of severe visceral failure, and to use it, in selected cases, only for periods not exceeding 48 hours.

摘要

在四年的时间里,16例弥漫性腹膜炎患者在重症监护病房接受了术后腹腔灌洗治疗。大多数病例为术后腹膜炎并伴有严重的脏器功能衰竭。含有抗菌剂的灌洗液以高流速(平均16.5升)灌注1至11天。该系列的总体死亡率极高(75%),如果仅考虑术后腹膜炎病例,死亡率更高(85%)。在再次手术或尸检时对腹膜进行的解剖检查显示,残留脓肿的发生率异常高。这些脓肿是感染持续或复发的原因,并解释了高死亡率。这些观察结果,再加上局部或全身并发症的频繁发生,导致作者拒绝在存在严重脏器功能衰竭的术后腹膜炎中使用腹腔灌洗,并仅在选定的病例中使用,且使用时间不超过48小时。

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