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老年寡转移性乳腺癌的立体定向消融放疗

Stereotactic ablative radiotherapy for oligometastatic breast cancer in elderly patients.

作者信息

Morales-Orue Ignacio, Zafra-Martin Juan, Garcia Laura, Chicas-Sett Rodolfo, Castilla-Martinez Juan, Cabezon Maria Auxiliadora, Burgos Javier, Lloret Marta, Lara Pedro C

机构信息

Department of Radiation Oncology, Punta de Europa Hospital, Algeciras, Spain.

Department of Medical Oncology, Punta de Europa Hospital, Algeciras, Spain.

出版信息

Transl Cancer Res. 2020 Jan;9(Suppl 1):S197-S206. doi: 10.21037/tcr.2019.08.29.

Abstract

Breast cancer (BC) is the principal cause of cancer-related death in women. Metastatic patients are usually treated with a systemic therapy, but clinical results are limited. Oligometastatic subjects can benefit from high-precision radiotherapy techniques to potentially achieve a complete response. Currently, there is limited evidence of stereotactic ablative radiotherapy (SABR) treatments in elderly oligometastatic cancer patients. A review of the medical literature was performed in PubMed database to assess the current role of SABR in the treatment of breast oligometastases in elderly patients. SABR represents a feasible and safe therapeutic approach in oligometastatic elderly BC patients. Further studies are required to establish the optimum patient selection and treatment scheme.

摘要

乳腺癌(BC)是女性癌症相关死亡的主要原因。转移性患者通常接受全身治疗,但临床效果有限。寡转移患者可受益于高精度放疗技术,有可能实现完全缓解。目前,关于老年寡转移癌患者接受立体定向消融放疗(SABR)治疗的证据有限。在PubMed数据库中对医学文献进行了综述,以评估SABR在老年患者乳腺寡转移治疗中的当前作用。SABR是老年寡转移BC患者一种可行且安全的治疗方法。需要进一步研究以确定最佳的患者选择和治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb38/8797947/213ff952011b/tcr-09-S1-S197-f1.jpg

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