Jahantabi Elham, Soleimanzadeh Farzin, Salehi-Pourmehr Hanieh, Saadat Mahsa Zehi, Nouri Maryam, Hajebrahimi Sakineh
Department of Urology, Tabriz University of Medical Sciences Faculty of Medicine, Tabriz, Iran;Clinical Research Development Unit, Tabriz University of Medical Sciences, Imam Reza General Hospital, Tabriz, Iran.
Department of Urology, Tabriz University of Medical Sciences Faculty of Medicine, Tabriz, Iran.
Turk J Urol. 2021 Nov;47(6):509-517. doi: 10.5152/tud.2021.21108.
To investigate an adapted enhanced recovery after surgery (ERAS) protocol in adult augmentation cystoplasty (AC).
A total of 33 consecutive cases with a history of refractory idiopathic detrusor overactivity (IDO) or neurogenic bladder (NGB) with low capacity, poor compliance, high sustained detrusor pressure, and whose previous therapeutic methods had failed were enrolled. The adapted ERAS fasting8 hours, high protein, low carbohydrate diet, antibiotics, did not use narcotics as much as possible during anesthesia, acetaminophen, early nasogastric tube removal, neostigmine injection postoperation, metoclopramide, early oral diet, and mobilization were applied, and morbidity and hospital stay duration were analyzed.
Twenty-two patients had IDO, and the remained cases were NGB or had low bladder capacity or compliance. The mean age of patients in the IDO group was higher than in NGB cases (P ¼ .020). Following the adapted ERAS protocol implementation, more than two-third of patients returned to a regular diet on the second day postoperation in both groups. The mean (SD) hospital stay duration was 7.7 (1.5) days. Postoperative fasting time was 8.8 6 3. 7 hours, and bowel function was returned 1 day postoperation in 82% of patients. Only 33.3% of adults need postprocedure acetaminophen for 2 days, and in 11 cases, it prescribed for 1 day. All subjects except paraplegic patients had early mobilization 1 day postoperation.
Our findings revealed that adapted ERAS protocol could be safe and effective in adult AC. It accompanied by few complications, reduced intestinal motility problems, and a short length of hospital stay.
探讨一种适用于成人膀胱扩大术(AC)的改良加速康复外科(ERAS)方案。
连续纳入33例有难治性特发性逼尿肌过度活动(IDO)或神经源性膀胱(NGB)病史的患者,这些患者膀胱容量小、顺应性差、逼尿肌持续压力高,且既往治疗方法均失败。采用改良的ERAS方案,包括禁食8小时、高蛋白低碳水化合物饮食、抗生素、麻醉期间尽量不使用麻醉剂、对乙酰氨基酚、早期拔除鼻胃管、术后注射新斯的明、甲氧氯普胺、早期经口进食和活动,并分析发病率和住院时间。
22例患者为IDO,其余病例为NGB或膀胱容量小或顺应性差。IDO组患者的平均年龄高于NGB组(P = 0.020)。实施改良的ERAS方案后,两组超过三分之二的患者在术后第二天恢复正常饮食。平均(标准差)住院时间为7.7(1.5)天。术后禁食时间为8.8±3.7小时,82%的患者术后1天肠道功能恢复。只有33.3%的成年人术后需要使用对乙酰氨基酚2天,11例患者使用1天。除截瘫患者外,所有受试者术后1天均早期活动。
我们的研究结果表明,改良的ERAS方案在成人AC中可能是安全有效的。它并发症少,肠道蠕动问题减少,住院时间短。