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埃及人群样本中,剥脱性二氧化碳激光与液氮冷冻疗法治疗斑秃的对比研究。

Comparative study of the use of fractional CO laser versus the use of liquid nitrogen cryotherapy in the treatment of alopecia areata in a sample of the Egyptian population.

作者信息

Nouh Ahmed H, Kadah Ahmed S, Said Marwa

机构信息

Faculty of Medicine, Al-Azhar University, Cairo, Egypt.

Al-Hussin University Hospital, Al-Azhar University, Cairo, Egypt.

出版信息

Dermatol Ther. 2022 Apr;35(4):e15358. doi: 10.1111/dth.15358. Epub 2022 Feb 16.

DOI:10.1111/dth.15358
PMID:35119705
Abstract

Alopecia areata (AA) is an autoimmune disease that is represented as patches of hair loss, fractional CO laser and cryotherapy are used to stimulate hair growth in patients of AA. Evaluation of fractional CO laser effect versus liquid nitrogen cryotherapy in the treatment of AA. Eighty patients presented with patches of AA. The first group consisted of 40 patients were treated with fractional CO laser, the second group also 40 patients were treated with cryotherapy. The efficacy of the treatment was statistically evaluated. A positive therapeutic response was noted in most patients by trichoscopy at the end of treatment, there was a decrease in exclamation mark hairs, yellow dots, black dots, broken hairs, and an increase in short vellus hair and circle hair of patients compared to baseline and control. No serious side effects were seen. Fractional CO laser and liquid nitrogen cryotherapy are considered a promising, safe, and effective treatment modality with the better result with CO laser.

摘要

斑秃(AA)是一种自身免疫性疾病,表现为脱发斑,剥脱性二氧化碳激光和冷冻疗法用于刺激斑秃患者头发生长。评估剥脱性二氧化碳激光与液氮冷冻疗法治疗斑秃的效果。80例斑秃患者。第一组40例患者接受剥脱性二氧化碳激光治疗,第二组40例患者接受冷冻疗法治疗。对治疗效果进行统计学评估。治疗结束时,通过毛发镜检查发现大多数患者有积极的治疗反应,与基线和对照组相比,患者的惊叹号样毛发、黄点、黑点、断发减少,短毳毛和圈状发增加。未观察到严重副作用。剥脱性二氧化碳激光和液氮冷冻疗法被认为是一种有前景、安全且有效的治疗方式,二氧化碳激光效果更佳。