帕金森病患者的地面行走与跑步机行走：速度与时空步态测量指标的关系。
Overground versus treadmill walking in Parkinson's disease: Relationship between speed and spatiotemporal gait metrics.
机构信息
Department of Neurology, University of Minnesota, 516 Delaware Street SE, Minneapolis, MN 55455, United States.
Department of Biomedical Engineering, University of Minnesota, 7-105 Hasselmo Hall, 312 Church Street SE, Minneapolis, MN 55455, United States; Department of Neurological Surgery, University of California, 521 Parnassus Ave, M779, San Francisco, CA 94143, United States.
出版信息
Gait Posture. 2022 Mar;93:96-101. doi: 10.1016/j.gaitpost.2022.01.020. Epub 2022 Jan 26.
BACKGROUND
Treadmills provide a safe and convenient way to study the gait of people with Parkinson's disease (PD), but outcome measures derived from treadmill gait may differ from overground walking.
OBJECTIVE
To investigate how the relationships between gait metrics and walking speed vary between overground and treadmill walking in people with PD and healthy controls.
METHODS
We compared 29 healthy controls to 27 people with PD in the OFF-medication state. Subjects first walked overground on an instrumented gait walkway, then on an instrumented treadmill at 85%, 100% and 115% of their overground walking speed. Average stride length and cadence were computed for each subject in both overground and treadmill walking.
RESULTS
Stride length and cadence both differed between overground and treadmill walking. Regressions of stride length and cadence on gait speed showed a log-log relationship for both overground and treadmill gait in both PD and control groups. The difference between the PD and control groups during overground gait was maintained for treadmill gait, not only when treadmill speed matched overground speed, but also with ± 15% variation in treadmill speed from that value.
SIGNIFICANCE
These results show that the impact of PD on stride length and cadence and their relationship to gait speed is preserved in treadmill as compared to overground walking. We conclude that a treadmill protocol is suitable for laboratory use in studies of PD gait therapeutics.
背景
跑步机为研究帕金森病（PD）患者的步态提供了安全便捷的方式，但跑步机步态得出的结果可能与地面行走不同。
目的
探究在 PD 患者和健康对照组中，跑步机和地面行走时步态参数与行走速度之间的关系有何不同。
方法
我们将 29 名健康对照者与 27 名未服药状态的 PD 患者进行了比较。受试者首先在带仪器的步态走道上进行地面行走，然后以 85%、100%和 115%的地面行走速度在带仪器的跑步机上行走。分别计算每位受试者在地面和跑步机行走时的平均步长和步频。
结果
步长和步频在地面和跑步机行走之间均有差异。PD 和对照组的地面和跑步机步态速度与步长和步频的回归都呈现出对数-对数关系。PD 组和对照组在地面行走时的差异在跑步机行走时得以维持，不仅在跑步机速度与地面速度匹配时如此，而且在跑步机速度相对于该值有±15%的变化时也是如此。
意义
这些结果表明，与地面行走相比，PD 对步长和步频的影响及其与行走速度的关系在跑步机上得到了保留。我们得出结论，跑步机方案适合用于 PD 步态治疗的实验室研究。
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