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新加坡一家亚急性老年病房的虚弱症患病率及其相关性。

Frailty prevalence and its associations in a subacute geriatric ward in Singapore.

机构信息

Department of Geriatric Medicine, Changi General Hospital, Singapore.

Medical Service, Saint Andrew's Community Hospital, Singapore.

出版信息

Singapore Med J. 2023 Mar;64(3):196-202. doi: 10.11622/smedj.2022020. Epub 2022 Feb 10.

Abstract

INTRODUCTION

Our aim was to study the prevalence of frailty and its associated factors in a subacute geriatric ward.

METHODS

This was a cross-sectional study of 167 participants between June 2018 and June 2019. Baseline demographics and participants' Mini Nutritional Assessment, Geriatric Depression Scale, Mini Mental State Examination, Charlson's Comorbidity Index and LACE index scores were obtained. Functional measurements such as modified Barthel's Index scores and hand grip strength (HGS) were taken. Frailty was assessed using the Clinical Frailty Scale (CFS) and the FRAIL scale. Data on history of healthcare utilisation, medications, length of stay, selected blood investigations and presence of geriatric syndromes were also collected.

RESULTS

The prevalence of pre-frailty (CFS 4) and frailty (CFS ≥ 5) was 16.2% and 63.4%, respectively. There were significant associations between CFS and age (pre-frail vs. non-frail: odds ratio [OR] 1.14, 95% confidence interval [CI] 1.04-1.25, P = 0.006; frail vs. non-frail: OR 1.08, 95% CI 1.01-1.15, P = 0.021), HGS at discharge (frail vs. non-frail: OR 0.90, 95% CI 0.82-0.99, P = 0.025), serum albumin (frail vs. non-frail: OR 0.90, 95% CI 0.82-0.99, P = 0.035) and the presence of urinary incontinence (frail vs. non-frail: OR 3.03, 95% CI 1.19-7.77, P = 0.021).

CONCLUSION

Frailty is highly prevalent in the subacute geriatric setting and has many associated factors. In this study, independent factors associated with frailty were age, HGS at discharge, serum albumin and urinary incontinence. This has implications for future resource allocation for frail older inpatients and may help direct further research to study the effectiveness of frailty-targeted interventions.

摘要

简介

我们的目的是研究亚急性老年病房衰弱的流行情况及其相关因素。

方法

这是一项 2018 年 6 月至 2019 年 6 月期间对 167 名参与者进行的横断面研究。获得了参与者的基线人口统计学资料和迷你营养评估、老年抑郁量表、简易精神状态检查、Charlson 合并症指数和 LACE 指数评分。进行了功能测量,如改良巴氏量表评分和握力(HGS)。使用临床虚弱量表(CFS)和 FRAIL 量表评估虚弱。还收集了医疗保健利用史、药物、住院时间、选定的血液检查和老年综合征的存在的数据。

结果

衰弱前期(CFS 4)和衰弱(CFS≥5)的患病率分别为 16.2%和 63.4%。CFS 与年龄(衰弱前期与非衰弱期:比值比[OR]1.14,95%置信区间[CI]1.04-1.25,P=0.006;衰弱与非衰弱期:OR 1.08,95%CI 1.01-1.15,P=0.021)、出院时的 HGS(衰弱:OR 0.90,95%CI 0.82-0.99,P=0.025)、血清白蛋白(衰弱:OR 0.90,95%CI 0.82-0.99,P=0.035)和尿失禁的存在(衰弱:OR 3.03,95%CI 1.19-7.77,P=0.021)显著相关。

结论

衰弱在亚急性老年病房中高度流行,并有许多相关因素。在这项研究中,与衰弱相关的独立因素是年龄、出院时的 HGS、血清白蛋白和尿失禁。这对未来虚弱老年住院患者的资源分配有影响,并可能有助于指导进一步研究,以研究针对虚弱的干预措施的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78e7/10071853/5c4608c99182/SMJ-64-196-g001.jpg

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