Suppr超能文献

使用超导隧道结低温检测对金(4-丁基苯硫醇盐)纳米团簇进行质谱分析揭示了独特的亚稳裂解。

Mass Spectrometry of Au(4-butylbenzenethiolate) Nanoclusters Using Superconducting Tunnel Junction Cryodetection Reveals Distinct Metastable Fragmentation.

作者信息

Plath Logan D, Abroshan Hadi, Zeng Chenjie, Kim Hyung J, Jin Rongchao, Bier Mark E

机构信息

Department of Chemistry, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, Pennsylvania 15213, United States.

Center for Molecular Analysis, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, Pennsylvania 15213, United States.

出版信息

J Am Soc Mass Spectrom. 2022 Mar 2;33(3):521-529. doi: 10.1021/jasms.1c00346. Epub 2022 Feb 11.

Abstract

Cryodetection mass spectrometry (MS) was used to study the Au(TBBT) (TBBT = 4-butylbenzenethiolate) catenane nanocluster. The matrix-assisted laser desorption ionization (MALDI) process generates distinct fragments that can be arranged into two distinct regimes: (i) in-source fragmentation, which occurs rapidly in a relatively short (<170 ns) time frame, and (ii) metastable fragmentation, which occurs postacceleration during a time-of-flight (TOF) mass analysis over a longer time frame (>170 ns-250 μs). Using MALDI-TOF MS with superconducting tunnel junction (STJ) cryodetection, distinct metastable nanocluster fragments were resolved at lower energies deposited into the detector. The results also demonstrated that STJ cryodetection MS can be used to acquire multiple (>10), simultaneous tandem mass spectra in a single experiment. Simulated fragmentation of the Au nanocluster using molecular dynamics (AIMD) revealed the different fragmentation processes and confirmed the MS results. Using both the empirical MS data and AIMD calculations, fragmentation pathways are proposed for Au(TBBT), which terminate with two small, stable ringed species.

摘要

采用低温检测质谱法(MS)对Au(TBBT)(TBBT = 4-丁基苯硫醇盐)连环纳米团簇进行了研究。基质辅助激光解吸电离(MALDI)过程产生了不同的碎片,这些碎片可分为两种不同的情况:(i)源内碎片化,在相对较短(<170 ns)的时间内快速发生;(ii)亚稳碎片化,在飞行时间(TOF)质量分析的加速后阶段,在较长时间(>170 ns - 250 μs)内发生。使用配备超导隧道结(STJ)低温检测的MALDI-TOF MS,在沉积到探测器的较低能量下分辨出了不同的亚稳纳米团簇碎片。结果还表明,STJ低温检测MS可用于在单个实验中获取多个(>10)同时的串联质谱。使用分子动力学(AIMD)对金纳米团簇进行模拟碎片化,揭示了不同的碎片化过程并证实了质谱结果。结合经验性的质谱数据和AIMD计算,提出了Au(TBBT)的碎片化途径,其最终形成两个小的、稳定的环状物种。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验