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病例报告:小切口微透镜取出术后妊娠期间双侧角膜扩张。

Case Report: Bilateral Corneal Ectasia Developed during Pregnancy after Small-incision Lenticule Extraction.

机构信息

Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.

Eye Center, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

出版信息

Optom Vis Sci. 2022 Jun 1;99(6):528-533. doi: 10.1097/OPX.0000000000001877. Epub 2022 Feb 11.

Abstract

SIGNIFICANCE

This case highlights that hormonal changes during pregnancy could affect the biomechanical stability of the cornea and lead to corneal ectasia during pregnancy after corneal refractive surgery.

PURPOSE

We report an unusual case of bilateral corneal ectasia after small-incision lenticule extraction that developed during pregnancy.

CASE REPORT

A 27-year-old woman experienced post-small-incision lenticule extraction corneal ectasia. Her pre-operative corneal topography was normal, with a minimum central corneal thickness of 538 μm in the right eye and 530 μm in the left eye. The manifest refraction was -7.75 -0.25 × 180 and -7.50 -0.75 × 10, and the lenticule thickness was 140 and 139 μm in the right and left eyes, respectively. After 11 months, in her first trimester, the patient began to experience gradually deteriorating blurred vision. Two years post-operatively, corneal ectasia was diagnosed based on topographic data. The automatic optometer examination was -7.25 -2.50 × 42 in the right eye and -11.00 -5.00 × 140 in the left eye. Later, the patient underwent corneal collagen cross-linking to control further progression and was recommended to wear rigid gas-permeable contact lenses.

CONCLUSIONS

Surgeons should be alert for cornea ectasia after refractive surgery in pregnant patients, as hormonal changes during pregnancy may affect corneal biomechanical stability.

摘要

意义

本病例强调了怀孕期间的激素变化可能会影响角膜的生物力学稳定性,并导致屈光手术后怀孕期间的角膜扩张。

目的

我们报告了一例小切口微透镜提取术后双侧角膜扩张的罕见病例,该病例发生在怀孕期间。

病例报告

一名 27 岁女性经历了小切口微透镜提取术后的角膜扩张。她的术前角膜地形图正常,右眼最小中央角膜厚度为 538μm,左眼为 530μm。明视屈光度为-7.75-0.25×180 和-7.50-0.75×10,微透镜厚度分别为右眼和左眼 140 和 139μm。11 个月后,在她的孕早期,患者开始逐渐出现视力模糊。术后 2 年,根据地形图数据诊断为角膜扩张。自动验光检查右眼为-7.25-2.50×42,左眼为-11.00-5.00×140。后来,患者接受了角膜胶原交联以控制进一步进展,并被建议佩戴硬性透气性隐形眼镜。

结论

外科医生应该警惕屈光手术后孕妇的角膜扩张,因为怀孕期间的激素变化可能会影响角膜的生物力学稳定性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afc4/9169746/8fd01072f1b2/ovs-99-528-g001.jpg

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