Department of Operative Dentistry and Dental Materials, School of Dentistry, Federal University of Uberlândia, Av Pará 1720, Block 4L, Campus Umuarama, Uberlândia, MG, 38405-320, Brazil.
Radiotherapy Sector, Clinical Hospital, Federal University of Triângulo Mineiro, Av Getúlio Guaritá 130, Uberaba, MG, 38025-440, Brazil.
Clin Oral Investig. 2022 Jun;26(6):4315-4325. doi: 10.1007/s00784-022-04395-z. Epub 2022 Feb 11.
To investigate the chemical changes in root dentin submitted to ionizing radiation and how it affects the interaction with resin cements.
Forty human premolars were randomly divided into two groups (n = 20): non-irradiated and irradiated. They were randomly subdivided according to the type of resin cement (n = 10): conventional (RelyX ARC, 3 M ESPE) or self-adhesive (RelyX U200, 3 M ESPE). After cementation of the fiberglass posts, the roots were sectioned to be analyzed by Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, and confocal laser scanning microscopy (CLSM). The data obtained from FTIR and Raman were analyzed using two-way ANOVA followed Tukey's test (α = 0.05). For CLSM, a descriptive analysis was performed.
In the FTIR, there was a significant difference between the non-irradiated and irradiated groups for phosphate (p = 0.011), carbonate (p < 0.001), amide III (p = 0.038), and carbonate/mineral ratio (p < 0.001). Regarding the root third, there was a difference for amide I (p = 0.002), mineral/matrix ratio (p = 0.001), and amide I/CH (p = 0.026) between the cervical and the others. Raman spectroscopy revealed no difference between groups for 961/1458 cm in the diffusion zone. CLSM showed a different interaction pattern for the two cements with the irradiated dentin from the cervical third.
Ionizing radiation altered the chemical composition of root dentin, especially in the cervical third. The resin cements showed less interaction with the irradiated root dentin.
As radiotherapy alters the chemical composition of root dentin, the interaction of resin cement with dentin can compromise the success of rehabilitation with fiberglass posts.
研究接受电离辐射的根管牙本质的化学变化及其对与树脂水门汀相互作用的影响。
四十颗人上颌前磨牙随机分为两组（n=20）：未照射组和照射组。根据树脂水门汀的类型（n=10）将其随机分为两组：传统型（RelyX ARC，3M ESPE）或自粘接型（RelyX U200，3M ESPE）。玻璃纤维桩黏固后，将牙根切成薄片，通过傅里叶变换红外光谱（FTIR）、拉曼光谱和共聚焦激光扫描显微镜（CLSM）进行分析。FTIR 和拉曼获得的数据采用双因素方差分析和 Tukey 检验（α=0.05）进行分析。CLSM 采用描述性分析。
在 FTIR 中，未照射组和照射组的磷酸盐（p=0.011）、碳酸盐（p<0.001）、酰胺 III（p=0.038）和碳酸盐/矿物质比值（p<0.001）有显著差异。关于牙根的第三个部分，颈部分叉处的酰胺 I（p=0.002）、矿物质/基质比值（p=0.001）和酰胺 I/CH（p=0.026）有差异。拉曼光谱显示，在扩散区的 961/1458cm 处，两组之间没有差异。CLSM 显示，两种水门汀与来自颈三分叉的照射牙本质的相互作用模式不同。
电离辐射改变了根管牙本质的化学成分，尤其是在颈三分叉处。树脂水门汀与照射后的牙本质的相互作用减少。
由于放射治疗改变了根管牙本质的化学成分，树脂水门汀与牙本质的相互作用可能会影响玻璃纤维桩修复的成功率。
Zotero 插件