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因药物治疗依从性差和复杂尿路感染引发的甲状腺危象成功得到控制:一例报告

Successful Stabilization of Thyroid Storm Precipitated by Medication Noncompliance and Complicated Urinary Tract Infection: A Case Report.

作者信息

Hunzeker Nicole K, Choudhury Abid

机构信息

Internal Medicine, Jamaica Hospital Medical Center, New York, USA.

出版信息

Cureus. 2022 Jan 9;14(1):e21048. doi: 10.7759/cureus.21048. eCollection 2022 Jan.

DOI:10.7759/cureus.21048
PMID:35155015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8824454/
Abstract

Thyroid storm is a rare but life-threatening condition that can occur in the setting of incompletely treated or untreated hyperthyroidism, and is often precipitated by recent infection, surgery, or trauma. We present a fascinating case report of the successful stabilization of a 29-year-old female, recently diagnosed with hyperthyroidism and non-compliant with medications, who presented with thyroid storm in the setting of sepsis secondary to right-sided pyelonephritis, non-ST-segment elevation myocardial infarction (NSTEMI) type 2, and hyperbilirubinemia. Management was further complicated by electrolyte imbalances secondary to severe diarrhea due to the thyroid storm and pancytopenia likely due to aggressive hydration. This case is demonstrative of the importance of early recognition, timely management, and patient education of life-threatening endocrine disorders such as severe thyrotoxicosis.

摘要

甲状腺危象是一种罕见但危及生命的疾病,可发生于未得到充分治疗或未治疗的甲状腺功能亢进症患者中,且常由近期感染、手术或创伤诱发。我们报告了一例引人关注的病例,一名29岁女性,近期诊断为甲状腺功能亢进症且未遵医嘱服药,因右侧肾盂肾炎继发脓毒症、2型非ST段抬高型心肌梗死(NSTEMI)和高胆红素血症而出现甲状腺危象,最终成功实现病情稳定。由于甲状腺危象导致严重腹泻继发电解质失衡,以及积极补液可能导致全血细胞减少,使得治疗进一步复杂化。该病例证明了早期识别、及时处理以及对严重甲状腺毒症等危及生命的内分泌疾病进行患者教育的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96d6/8824454/e66d788d4cdf/cureus-0014-00000021048-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96d6/8824454/80c2baf06f83/cureus-0014-00000021048-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96d6/8824454/6f3ab1aad062/cureus-0014-00000021048-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96d6/8824454/7e66e956533c/cureus-0014-00000021048-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96d6/8824454/d5c615b7d3db/cureus-0014-00000021048-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96d6/8824454/e66d788d4cdf/cureus-0014-00000021048-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96d6/8824454/80c2baf06f83/cureus-0014-00000021048-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96d6/8824454/6f3ab1aad062/cureus-0014-00000021048-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96d6/8824454/7e66e956533c/cureus-0014-00000021048-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96d6/8824454/d5c615b7d3db/cureus-0014-00000021048-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96d6/8824454/e66d788d4cdf/cureus-0014-00000021048-i05.jpg