Conte H R, Plutchik R, Wild K V, Karasu T B
Arch Gen Psychiatry. 1986 May;43(5):471-9. doi: 10.1001/archpsyc.1986.01800050077009.
To determine whether combined psychotherapy and pharmacotherapy is superior to alternative therapies for unipolar depression, we reviewed all controlled studies of outpatients treated for unipolar depression reported between 1974 and 1984. To accomplish this, we developed a new statistical approach that is specific in its method of evaluating the quality of each study and specific about the weights given to each outcome. The combined active treatments (drugs plus psychotherapy) were appreciably more effective than the placebo conditions but only slightly superior to psychotherapy alone, pharmacotherapy alone, or either of these combined with a placebo.
为了确定联合心理治疗和药物治疗对于单相抑郁症是否优于其他替代疗法，我们回顾了1974年至1984年间报道的所有关于单相抑郁症门诊患者治疗的对照研究。为实现这一目的，我们开发了一种新的统计方法，该方法在评估每项研究质量的方法上具有特异性，并且在赋予每个结果的权重方面也很明确。联合积极治疗（药物加心理治疗）明显比安慰剂组更有效，但仅略优于单独的心理治疗、单独的药物治疗或这些与安慰剂联合使用的任何一种。
