Department of Infectious Diseases, Fujita Health University School of Medicine, Aichi, Japan.
Department of Infectious Diseases, Fujita Health University School of Medicine, Aichi, Japan.
J Infect Chemother. 2022 Jun;28(6):828-832. doi: 10.1016/j.jiac.2022.01.020. Epub 2022 Feb 11.
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) can cause a wide variety of infections, ranging from skin and soft tissue infections to life-threatening invasive diseases such as necrotizing pneumonia and infective endocarditis. Here, we present a case of a healthy young female presenting with fever, headache and nausea, who was diagnosed with mitral valve infective endocarditis due to CA-MRSA and whose course was complicated by meningitis and multiple septic emboli. The causative MRSA strain belonged to sequence type 97 and harbored SCCmec Ⅳc but not lukS/F-PV genes. ST97, which is frequently isolated from livestock animals and known as a common lineage of livestock-associated MRSA, may cause invasive infection in the community.
社区相关性耐甲氧西林金黄色葡萄球菌（CA-MRSA）可引起多种感染，从皮肤和软组织感染到危及生命的侵袭性疾病，如坏死性肺炎和感染性心内膜炎。在这里，我们报告了一例健康年轻女性出现发热、头痛和恶心，因 CA-MRSA 导致二尖瓣感染性心内膜炎，其病程并发脑膜炎和多发脓毒性栓子。致病的耐甲氧西林金黄色葡萄球菌菌株属于序列类型 97，携带 SCCmec Ⅳc 但不携带 lukS/F-PV 基因。ST97 常从家畜动物中分离出来，被认为是家畜相关耐甲氧西林金黄色葡萄球菌的常见谱系，可能会在社区引起侵袭性感染。
