头孢哌酮钠舒巴坦钠的体内抗菌活性。头孢哌酮钠舒巴坦钠与人多形核白细胞杀菌作用的协同性
[In vivo antibacterial activity of cefbuperazone. Synergy of cefbuperazone for bactericidal effect with human polymorphonuclear leukocytes].
作者信息
Kumasaka Y, Nakahata H, Hirai Y, Imamura K, Takebe K, Suzuki I, Senda H
出版信息
Jpn J Antibiot. 1986 Jan;39(1):154-8.
PMID:3517405
Abstract
Studies were done utilizing E. coli No. 59 which are resistant against human and mouse serum, and the following results were obtained. The therapeutic effect of cefbuperazone (CPBZ) against systemic infections of mice was much higher than that of cefmetazole (CMZ), cefotetan (CTT), latamoxef (LMOX) and cefoperazone (CPZ). Synergistic bactericidal effect with human polymorphonuclear leukocytes was more marked for CBPZ than CMZ.
摘要
利用对人和小鼠血清具有抗性的大肠杆菌59号进行了研究，并获得了以下结果。头孢哌酮（CPBZ）对小鼠全身感染的治疗效果远高于头孢美唑（CMZ）、头孢替坦（CTT）、拉氧头孢（LMOX）和头孢哌酮（CPZ）。与头孢美唑相比，头孢哌酮与人多形核白细胞的协同杀菌作用更为显著。
Zotero 插件