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南非公共医疗体系中的高血压:疾病成本和疾病负担研究。

Hypertension in the South African public healthcare system: a cost-of-illness and burden of disease study.

机构信息

SAMRC/Wits Centre for Health Economics and Decision Science, PRICELESS, University of the Witwatersrand, Faculty of Health Sciences, Johannesburg, Gauteng, South Africa

Center for Health Services & Outcomes Research, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

出版信息

BMJ Open. 2022 Feb 22;12(2):e055621. doi: 10.1136/bmjopen-2021-055621.

Abstract

OBJECTIVES

To quantify the health and economic burden of hypertension in the South African public healthcare system.

SETTING

All inpatient, outpatient and rehabilitative care received in the national public healthcare system.

PARTICIPANTS

Adults, aged ≥20 years, who receive care in the public healthcare system.

OUTCOMES

Worksheet-based models synthesised data from multiple sources to estimate the burden of disease, direct healthcare costs, and societal costs associated with hypertension. Results were disaggregated by sex.

RESULTS

Approximately 8.22 million (30.8%, 95% CI 29.5% to 32.1%) South African adults with no private health insurance have hypertension. Hypertension was estimated to cause 14 000 (95% CI 11 100 to 17 200) ischaemic heart disease events, 13 300 (95% CI 10 600 to 16 300) strokes and 6100 (95% CI 4970 to 7460) cases of chronic kidney disease annually. Rates of hypertension, hypertension-related stroke and hypertension-related chronic kidney disease were greater for women compared with men.The direct healthcare costs associated with hypertension were estimated to be ZAR 10.1 billion (95% CI 8.98 to 11.3 billion) or US$0.711 billion (95% CI 0.633 to 0.793 billion). Societal costs were estimated to be ZAR 29.4 billion (95% CI 26.0 to 33.2 billion) or US$2.08 billion (95% CI 1.83 to 2.34 billion). Direct healthcare costs were greater for women (ZAR 6.11 billion or US$0.431 billion) compared with men (ZAR 3.97 billion or US$0.280 billion). Conversely, societal costs were lower for women (ZAR 10.5 billion or US$0.743 billion) compared with men (ZAR 18.9 billion or US$1.33 billion).

CONCLUSION

Hypertension exerts a heavy health and economic burden on South Africa. Establishing cost-effective best practice guidelines for hypertension treatment requires further research. Such research will be essential if South Africa is to make progress in its efforts to implement universal healthcare.

摘要

目的

量化南非公共医疗体系中高血压的健康和经济负担。

设定

国家公共医疗体系中所有的住院、门诊和康复护理。

参与者

在公共医疗体系中接受治疗的 20 岁及以上成年人。

结果

基于工作表的模型综合了来自多个来源的数据,以估计疾病负担、直接医疗成本以及与高血压相关的社会成本。结果按性别进行了细分。

结果

大约有 822 万(30.8%,95%置信区间 29.5%至 32.1%)没有私人医疗保险的南非成年人患有高血压。高血压估计每年导致 14000 例(95%置信区间 11100 至 17200)缺血性心脏病事件、13300 例(95%置信区间 10600 至 16300)中风和 6100 例(95%置信区间 4970 至 7460)慢性肾脏病。与男性相比,女性的高血压、高血压相关中风和高血压相关慢性肾脏病的发病率更高。高血压相关的直接医疗成本估计为 101 亿南非兰特(95%置信区间 89.8 亿至 11.3 亿)或 7.11 亿美元(95%置信区间 6.33 亿至 7.93 亿美元)。社会成本估计为 294 亿南非兰特(95%置信区间 26.0 亿至 33.2 亿)或 20.8 亿美元(95%置信区间 18.3 亿至 23.4 亿美元)。与男性(61.1 亿南非兰特或 4.31 亿美元)相比,女性(39.7 亿南非兰特或 2.80 亿美元)的直接医疗成本更高。相反,与男性(105 亿南非兰特或 74.3 亿美元)相比,女性(105 亿南非兰特或 74.3 亿美元)的社会成本更低。189 亿南非兰特或 1.33 亿美元)。

结论

高血压给南非带来了沉重的健康和经济负担。制定具有成本效益的高血压治疗最佳实践指南需要进一步研究。如果南非要在努力实现全民医疗保健方面取得进展,这种研究将是必不可少的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae5/8867372/f298edb7c372/bmjopen-2021-055621f01.jpg

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