新型冠状病毒肺炎（COVID-19）儿童神经肌肉表现及既往神经肌肉疾病管理的综合综述
A Comprehensive Review of Neuromuscular Manifestations of COVID-19 and Management of Pre-Existing Neuromuscular Disorders in Children.
作者信息
Goetschius Daniel J, Kim Yunsung, Kumar Ashutosh, Paul Dustin, Naik Sunil
机构信息
Penn State College of Medicine Medical Scientist Training Program, Hershey, PA 17033, USA.
Department of Pediatrics and Neurology, Penn State Health Children's Hospital, Penn State College of Medicine, Hershey, PA 17033, USA.
出版信息
J Clin Med. 2022 Feb 11;11(4):934. doi: 10.3390/jcm11040934.
Since the emergence of SARS-CoV-2, several studies have been published describing neuromuscular manifestations of the disease, as well as management of pre-existing pediatric neuromuscular disorders during the COVID-19 pandemic. These disorders include muscular dystrophies, myasthenic syndromes, peripheral nerve disorders, and spinal muscular atrophy. Such patients are a vulnerable population due to frequent complications such as scoliosis, cardiomyopathy, and restrictive lung disease that put them at risk of severe complications of COVID-19. In this review, neuromuscular manifestations of COVID-19 in children and the management of pre-existing pediatric neuromuscular disorders during the COVID-19 pandemic are discussed. We also review strategies to alleviate pandemic-associated disruptions in clinical care and research, including the emerging role of telemedicine and telerehabilitation to address the continued special needs of these patients.
自严重急性呼吸综合征冠状病毒2（SARS-CoV-2）出现以来，已有多项研究发表，描述了该疾病的神经肌肉表现，以及在冠状病毒病（COVID-19）大流行期间对既往存在的儿童神经肌肉疾病的管理。这些疾病包括肌营养不良症、肌无力综合征、周围神经疾病和脊髓性肌萎缩症。由于频繁出现脊柱侧弯、心肌病和限制性肺病等并发症，这类患者属于弱势群体，这些并发症使他们面临COVID-19严重并发症的风险。在这篇综述中，讨论了儿童COVID-19的神经肌肉表现以及在COVID-19大流行期间对既往存在的儿童神经肌肉疾病的管理。我们还回顾了减轻大流行相关临床护理和研究中断的策略，包括远程医疗和远程康复在满足这些患者持续特殊需求方面的新作用。
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