Children's Wisconsin, 999 North 92nd Street, Suite C320, Milwaukee, WI 53226, USA.
Department of Pediatric Neurosurgery, Children's Wisconsin, 8915 W. Connell Court, Milwaukee, WI 53226, USA.
Clin Perinatol. 2022 Mar;49(1):267-277. doi: 10.1016/j.clp.2021.11.015. Epub 2022 Jan 21.
Fetal surgery is a constantly evolving field that showed noticeable progress with the treatment of myelomeningocele (MMC) using prenatal repair. Despite this success, there are ongoing questions regarding the optimal approach for fetal myelomeningocele repair, as well as which patients are eligible. Expansion of the inclusion and exclusion criteria is an important ongoing area of study for myelomeningocele including the recent Management of Myelomeningocele Plus trial. The significant personal and financial burden required of families seeking treatment has likely limited its accessibility to the general population.
胎儿手术是一个不断发展的领域,通过产前修复治疗脊髓脊膜膨出(MMC)取得了显著进展。尽管取得了这一成功,但对于胎儿脊髓脊膜膨出修复的最佳方法以及哪些患者符合条件,仍存在持续的问题。包括最近的脊髓脊膜膨出加管理试验在内的脊髓脊膜膨出纳入和排除标准的扩展是一个正在进行的重要研究领域。寻求治疗的家庭需要承担巨大的个人和经济负担,这可能限制了其在普通人群中的可及性。