Kunwald Mikkel, Straszek Christian Lund, Bjarkam Carsten Reidies, Ettrup Marianne Schmidt, Skajaa Torjus, Thomsen Janus Laust, Thusgaard Mikkel, Steiness Morten Zebitz
Department of Neurosurgery, Aalborg University Hospital, Aalborg, Denmark.
Center for General Practice, Aalborg University, Aalborg, Denmark.
Adolesc Health Med Ther. 2022 Feb 15;13:39-43. doi: 10.2147/AHMT.S349975. eCollection 2022.
A 15-year-old female experiencing lumbar pain without prior trauma. Despite being prescribed strong analgesics by her family physician, the symptoms intensified, and she was referred to diagnostic imaging. Magnetic resonance imaging revealed an intradural extramedullary tumor in the spinal canal, located behind the L3 corpora. The patient underwent neurosurgery with a complete resection of the tumor. The histopathologic examination revealed Ewing sarcoma by identifying EWSR1 gene in the extracted tissue. The patient was subsequently referred for extensive specialized oncological treatment including photon irradiation therapy and chemotherapy. Thirty-six months on from the initial diagnosis, the patient is doing well and suffers no sequelae apart from hypogonadism.
一名15岁女性,无既往创伤史,却出现腰痛症状。尽管家庭医生为她开了强效镇痛药,但症状仍加剧,随后她被转诊至诊断影像科。磁共振成像显示椎管内硬膜内髓外肿瘤,位于L3椎体后方。患者接受了神经外科手术,肿瘤被完全切除。组织病理学检查通过在提取组织中鉴定EWSR1基因,确诊为尤因肉瘤。患者随后被转诊接受包括光子放射治疗和化疗在内的广泛专业肿瘤治疗。自初次诊断起36个月后,患者情况良好,除性腺功能减退外无其他后遗症。