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肿瘤护理模式对癌症治疗期间支持性护理药物使用的影响。

Impact of the Oncology Care Model on Use of Supportive Care Medications During Cancer Treatment.

作者信息

Brooks Gabriel A, Landrum Mary Beth, Kapadia Nirav S, Liu Pang-Hsiang, Wolf Robert, Riedel Lauren E, Hsu Van Doren, Jhatakia Parekh Shalini, Simon Carol, Hassol Andrea, Keating Nancy L

机构信息

Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine, Lebanon, NH.

Department of Health Care Policy, Harvard Medical School, Boston, MA.

出版信息

J Clin Oncol. 2022 Jun 1;40(16):1763-1771. doi: 10.1200/JCO.21.02342. Epub 2022 Feb 25.

Abstract

PURPOSE

The Oncology Care Model (OCM) is an episode-based alternative payment model for cancer care that seeks to reduce Medicare spending while maintaining care quality. We evaluated the impact of OCM on appropriate use of supportive care medications during cancer treatment.

METHODS

We evaluated chemotherapy episodes assigned to OCM (n = 201) and comparison practices (n = 534) using Medicare claims (2013-2019). We assessed denosumab use for beneficiaries with bone metastases from breast, lung, or prostate cancer; prophylactic WBC growth factor use for beneficiaries receiving chemotherapy for breast, lung, or colorectal cancer; and prophylactic use of neurokinin-1 (NK1) antagonists and long-acting serotonin antagonists for beneficiaries receiving chemotherapy for any cancer type. Analyses used a difference-in-difference approach.

RESULTS

After its launch in 2016, OCM led to a relative reduction in the use of denosumab for beneficiaries with bone metastases receiving bone-modifying medications (eg, 5.0 percentage point relative reduction in breast cancer episodes [90% CI, -7.1 to -2.8]). There was no OCM impact on use of prophylactic WBC growth factors during chemotherapy with high or low risk for febrile neutropenia. Among beneficiaries receiving chemotherapy with intermediate febrile neutropenia risk, OCM led to a 7.6 percentage point reduction in the use of prophylactic WBC growth factors during breast cancer episodes (90% CI, -12.6 to -2.7); there was no OCM impact in lung or colorectal cancer episodes. Among beneficiaries receiving chemotherapy with high or moderate emetic risk, OCM led to reductions in the prophylactic use of NK1 antagonists and long-acting serotonin antagonists (eg, 6.0 percentage point reduction in the use of NK1 antagonists during high emetic risk chemotherapy [90% CI, -9.0 to -3.1]).

CONCLUSION

OCM led to the reduced use of some high-cost supportive care medications, suggesting more value-conscious care.

摘要

目的

肿瘤护理模式(OCM)是一种基于诊疗期间的癌症护理替代支付模式,旨在在维持护理质量的同时减少医疗保险支出。我们评估了OCM对癌症治疗期间支持性护理药物合理使用的影响。

方法

我们使用医疗保险理赔数据(2013 - 2019年)评估了分配到OCM的化疗诊疗期间(n = 201)和对照医疗机构(n = 534)。我们评估了地诺单抗在患有来自乳腺癌、肺癌或前列腺癌骨转移的受益人中的使用情况;预防性白细胞生长因子在接受乳腺癌、肺癌或结直肠癌化疗的受益人中的使用情况;以及神经激肽-1(NK1)拮抗剂和长效5-羟色胺拮抗剂在接受任何癌症类型化疗的受益人中的预防性使用情况。分析采用了双重差分法。

结果

2016年推出后,OCM导致接受骨改良药物治疗的骨转移受益人对地诺单抗的使用相对减少(例如,乳腺癌诊疗期间相对减少5.0个百分点[90%CI,-7.1至-2.8])。对于发热性中性粒细胞减少风险高或低的化疗,OCM对预防性白细胞生长因子的使用没有影响。在发热性中性粒细胞减少风险中等的接受化疗的受益人中,OCM导致乳腺癌诊疗期间预防性白细胞生长因子的使用减少7.6个百分点(90%CI,-12.6至-2.7);在肺癌或结直肠癌诊疗期间没有OCM影响。在呕吐风险高或中等的接受化疗的受益人中,OCM导致NK1拮抗剂和长效5-羟色胺拮抗剂的预防性使用减少(例如,高呕吐风险化疗期间NK1拮抗剂的使用减少6.0个百分点[90%CI,-9.0至-3.1])。

结论

OCM导致一些高成本支持性护理药物的使用减少,表明护理更具价值意识。

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