Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela 769008, India.
Department of Physics and Biophysics, Faculty of Food Science and Nutrition, Poznań University of Life Sciences, Wojska Polskiego 38/42, 60-637 Poznan, Poland.
Nutrients. 2022 Feb 19;14(4):885. doi: 10.3390/nu14040885.
The effect of coffee (caffeinated) on electro-cardiac activity is not yet sufficiently researched. In the current study, the occurrence of coffee-induced short-term changes in electrocardiogram (ECG) signals was examined. Further, a machine learning model that can efficiently detect coffee-induced alterations in cardiac activity is proposed. The ECG signals were decomposed using three different joint time-frequency decomposition methods: empirical mode decomposition, discrete wavelet transforms, and wavelet packet decomposition with varying decomposition parameters. Various statistical and entropy-based features were computed from the decomposed coefficients. The statistical significance of these features was computed using Wilcoxon's signed-rank (WSR) test for significance testing. The results of the WSR tests infer a significant change in many of these parameters after the consumption of coffee (caffeinated). Further, the analysis of the frequency bands of the decomposed coefficients reveals that most of the significant change was localized in the lower frequency band (<22.5 Hz). Herein, the performance of nine machine learning models is compared and a gradient-boosted tree classifier is proposed as the best model. The results suggest that the gradient-boosted tree (GBT) model that was developed using a db2 mother wavelet at level 2 decomposition shows the highest mean classification accuracy of 78%. The outcome of the current study will open up new possibilities in detecting the effects of drugs, various food products, and alcohol on cardiac functionality.
咖啡(含咖啡因)对心电活动的影响尚未得到充分研究。在当前的研究中,检查了咖啡引起的心电图(ECG)信号的短期变化的发生。此外,提出了一种能够有效检测咖啡引起的心脏活动改变的机器学习模型。使用三种不同的联合时频分解方法对 ECG 信号进行分解:经验模态分解、离散小波变换和具有不同分解参数的小波包分解。从分解系数中计算出各种基于统计和熵的特征。使用 Wilcoxon 的符号秩(WSR)检验对这些特征的统计显著性进行了计算。WSR 检验的结果推断出,在摄入咖啡(含咖啡因)后,许多这些参数发生了显著变化。此外,对分解系数的频带的分析表明,大多数显著变化都集中在低频带(<22.5 Hz)。在此,比较了九种机器学习模型的性能,并提出了梯度提升树分类器作为最佳模型。结果表明,使用 db2 母小波在 2 级分解时开发的梯度提升树(GBT)模型显示出最高的平均分类准确性为 78%。本研究的结果将为检测药物、各种食品和酒精对心脏功能的影响开辟新的可能性。