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单中心经验表明,前副隐静脉内热消融安全且有效。

A single-center experience of anterior accessory saphenous vein endothermal ablation demonstrates safety and efficacy.

机构信息

New York University Langone Health, New York, NY.

New York University Grossman School of Medicine, New York, NY.

出版信息

J Vasc Surg Venous Lymphat Disord. 2022 Sep;10(5):993-998. doi: 10.1016/j.jvsv.2022.02.009. Epub 2022 Feb 24.

DOI:10.1016/j.jvsv.2022.02.009
PMID:35218957
Abstract

OBJECTIVE

Endothermal ablation is well-established for the treatment of the great and small saphenous veins. Data are lacking for treatment of the anterior accessory saphenous vein (AASV). The purpose of this study was to evaluate the safety and efficacy of AASV treatment using endothermal ablation.

METHODS

This retrospective review included 314 limbs at a single academic institution from 2016 to 2018 using the institutional Vascular Quality Initiative database. All limbs had documented AASV reflux. Baseline characteristics were evaluated including age; sex; ethnicity; clinical, etiology, anatomy, pathophysiology classification; Venous Clinical Severity Score (VCSS); and vein diameter. Outcomes relating to procedure safety and efficacy included treatment modality and length, successful ablation on postoperative imaging, postprocedural clinical outcomes, incidence of endothermal heat-induced thrombosis (EHIT), and any postprocedural complication.

RESULTS

A total of 314 consecutive limbs were identified from 2016 to 2018. The preprocedure VCSS scores were available for 312 limbs and averaged 6.13 ± 3.33. A history of varicose veins were reported in all limbs with 49.4% (n = 155) having previously undergone a procedure. The most common presenting symptom was mild edema in 52.5% (n = 165). Vein diameter and assessment of reflux were obtained by venous duplex ultrasound (DUS) examination. The largest AASV diameter was available for 304 limbs, averaging 7.93 ± 2.69 mm. Treatment modalities included radiofrequency ablation (RFA) in 59.2% (n = 186), endovenous laser ablation (EVLA) in 37.9% (n = 119), and isolated microphlebectomy in 2.9% (n = 9). In all, 38.5% (n = 121) of limbs underwent concomitant microphlebectomy at the time of EVLA. The total treatment length was obtained in 297 limbs, averaging 23.0 cm ± 12.0. Postoperatively, 94.6% of limbs (n = 297) were prescribed compression stockings. Postoperative DUS examination was performed in 312 limbs, revealing successful ablation in 96.5% (n = 303) with 2 limbs (0.6%) developing an EHIT, both treated with therapeutic enoxaparin for 1 week. Repeat DUS examination revealed thrombus resolution in one limb; the other patient was lost to follow-up. VCSS scores after the procedure were available for 145 limbs and averaged 4.45 ± 2.31. This was a statistically significant decrease from preprocedure VCSS scores (P < .01). Average duration of follow-up was 2.2 years, with two limbs lost to follow-up. Of the nine limbs (3.5%) whose initial procedure failed, five (56%) were treated using RFA and four (44%) were treated using EVLA. There were no other postoperative complications.

CONCLUSIONS

Our experience over a 3-year period for treating the AASV shows it to be safe and effective in a broad range of disease severity with an improvement in VCSS and a low incidence of EHIT. Additionally, RFA and EVLA exhibit similar treatment efficacy. Long-term follow-up data are needed.

摘要

目的

热消融术已广泛应用于大、小隐静脉的治疗。然而,对于前副隐静脉(AASV)的治疗,相关数据仍较为缺乏。本研究旨在评估应用热消融术治疗 AASV 的安全性和疗效。

方法

本回顾性研究纳入了 2016 年至 2018 年在某一学术机构中使用血管质量倡议(VQI)机构数据库的 314 条肢体。所有肢体均有记录的 AASV 反流。评估的基线特征包括年龄、性别、种族、临床、病因、解剖、病理生理学分类、静脉临床严重程度评分(VCSS)和静脉直径。与手术安全性和疗效相关的结果包括治疗方式和长度、术后影像学显示的成功消融、术后临床结果、热诱导血栓形成(EHIT)的发生率以及任何术后并发症。

结果

2016 年至 2018 年共确定了 314 条连续肢体。312 条肢体有术前 VCSS 评分,平均为 6.13±3.33。所有肢体均有静脉曲张病史,其中 49.4%(n=155)曾接受过治疗。最常见的首发症状为 52.5%(n=165)的轻度水肿。静脉直径和反流评估均通过静脉双功能超声(DUS)检查获得。304 条肢体获得了最大 AASV 直径,平均为 7.93±2.69mm。治疗方式包括射频消融(RFA)59.2%(n=186)、腔内激光消融(EVLA)37.9%(n=119)和单纯微静脉切除术 2.9%(n=9)。总共 38.5%(n=121)的肢体在接受 EVLA 治疗的同时进行了微静脉切除术。297 条肢体的总治疗长度,平均为 23.0±12.0cm。术后 94.6%(n=297)的肢体使用了压缩袜。312 条肢体进行了术后 DUS 检查,96.5%(n=303)显示成功消融,2 条肢体(0.6%)发生 EHIT,均采用依诺肝素钠治疗 1 周。再次进行 DUS 检查发现 1 条肢体血栓溶解,另 1 例患者失访。145 条肢体术后 VCSS 评分可获得,平均为 4.45±2.31。与术前 VCSS 评分相比,这一评分显著降低(P<0.01)。平均随访时间为 2.2 年,有两条肢体失访。在初始治疗失败的 9 条肢体中(3.5%),5 条(56%)采用 RFA 治疗,4 条(44%)采用 EVLA 治疗。无其他术后并发症。

结论

本研究为期 3 年,结果表明,治疗 AASV 安全有效,适用于多种严重程度的疾病,术后 VCSS 评分改善,EHIT 发生率低。此外,RFA 和 EVLA 显示出相似的治疗效果。需要长期随访数据。

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