Glaucoma Services, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India.
Wills Eye Hospital, Glaucoma Research Center, Philadelphia, PA, USA.
Indian J Ophthalmol. 2022 Mar;70(3):839-845. doi: 10.4103/ijo.IJO_1791_21.
To report the outcomes of pars plana insertion of Aurolab aqueous drainage implant (AADI) in adults with refractory glaucoma by the novel technique of making scleral tunnel instead of patch graft to cover the tube to prevent its migration.
A retrospective study was done between April 2016 and April 2018 on patients with ≥12 months of follow-up. The main outcome measure was a surgical failure at 12 months. The failure was defined as intraocular pressure (IOP) >18 mmHg or IOP ≤5 mmHg on two consecutive follow-up visits after 3 months, reoperation for glaucoma, loss of light perception vision, or implant explantation. Alternate definitions of failure including IOP >21 and IOP >15 mmHg were also considered.
: The study included 32 eyes of 32 patients. The mean age was 46.2 ± 17.5 years. The most common etiology is traumatic glaucoma (12 eyes, 37.5%). The mean preoperative IOP and anti-glaucoma medications were 43.3 ± 10.3 and 3.4 ± 0.5 mmHg, respectively; both the parameters at the final follow-up were reduced to 15.2 ± 8.1 and 1.6 ± 0.5 mmHg. The Kaplan-Meier survival estimates demonstrated that the cumulative probability of failure was 15.6% (95% CI; 6.8-33.5%) at 3 months, 18.7% (95% CI; 8.9-37.0%) at 6 months, and 25.0% (95% CI; 13.4-43.8%) at 12 months.
Pars plana AADI implantation with a newer modification technique is a useful procedure in reducing IOP and the number of anti-glaucoma medications in the eyes with refractory glaucoma. The visual acuity may be stabilized with the concurrent treatment of posterior segment pathology.
通过制作巩膜隧道而不是贴片移植物覆盖管来防止其迁移的新方法,报告在难治性青光眼成人中使用 Aurolab 水引流植入物(AADI)进行后房插入的结果。
对 2016 年 4 月至 2018 年 4 月间随访时间≥12 个月的患者进行回顾性研究。主要观察指标为 12 个月时手术失败。手术失败定义为:术后 3 个月后连续两次随访眼压(IOP)>18mmHg 或 IOP≤5mmHg、青光眼再次手术、光感视力丧失或植入物取出。还考虑了其他失败定义,包括 IOP>21mmHg 和 IOP>15mmHg。
研究共纳入 32 例 32 只眼。平均年龄为 46.2±17.5 岁。最常见的病因是外伤性青光眼(12 只眼,37.5%)。术前平均眼压和抗青光眼药物分别为 43.3±10.3mmHg 和 3.4±0.5mmHg,最终随访时分别降至 15.2±8.1mmHg 和 1.6±0.5mmHg。Kaplan-Meier 生存估计表明,术后 3 个月、6 个月和 12 个月时失败累积概率分别为 15.6%(95%CI:6.8-33.5%)、18.7%(95%CI:8.9-37.0%)和 25.0%(95%CI:13.4-43.8%)。
使用较新改良技术进行后房 AADI 植入是一种降低难治性青光眼患者眼压和抗青光眼药物数量的有效方法。通过同时治疗后节病变,可以稳定视力。