COVID-19 大流行对法国生育力保存活动的影响：法国卵巢和睾丸保存研究和研究组（GRECOT）的调查。

Impact of the COVID-19 pandemic on fertility preservation activities in France: A survey by the Groupe de Recherche et d'Etude sur la Conservation Ovarienne et Testiculaire (GRECOT; group for research and studies on ovarian and testicular preservation).

机构信息

Department of Reproductive Biology and Medicine, Cryobiology - University Hospital, 25030 Besançon, France; Bourgogne Franche-Comté University, and INSERM UMR1098 RIGHT, CIC-1431, 25030 Besançon, France.

Department of Obstetric Gynaecology, Strasbourg University Hospitals, 67300 Schiltigheim, France.

出版信息

J Gynecol Obstet Hum Reprod. 2022 Apr;51(4):102346. doi: 10.1016/j.jogoh.2022.102346. Epub 2022 Feb 25.

DOI:10.1016/j.jogoh.2022.102346

PMID:35227936

Abstract

BACKGROUND

To study the repercussions of the COVID-19 pandemic for fertility preservation activities in France.

BASIC PROCEDURES

A questionnaire was sent to all the fertility preservation centres, requesting, for fertility preservation techniques (gamete and gonadal tissue preservation), the number of patients managed before, during and after the lockdown, and the number of patients who were not able to have access to these techniques and thus suffered definitive losses of fertility, during the lockdown period in spring 2020.

MAIN FINDINGS

Fertility preservation activities in France did not cease entirely during the lockdown, but a 42.6% decrease in activity was observed. After lockdown, the levels of sperm, testicular and ovarian tissue cryopreservation returned to pre-lockdown levels (95.2%). The restoration of activity was partial only for oocyte freezing, which reached a level 56.8% that before lockdown. In total, 45 patients (8.35%) lost all chance of fertility preservation during the lockdown period.

PRINCIPAL CONCLUSIONS

In France, fertility preservation activities were significantly affected by the lockdown in spring 2020 linked to the COVID-19 pandemic.

摘要

背景

研究 COVID-19 大流行对法国生育力保存活动的影响。

基本程序

向所有生育力保存中心发送了一份问卷，要求他们报告在封锁期间、封锁期间和封锁解除后管理的接受生育力保存技术（配子和性腺组织保存）的患者人数，以及在 2020 年春季封锁期间无法获得这些技术而导致生育力永久丧失的患者人数。

主要发现

法国的生育力保存活动在封锁期间并未完全停止，但活动减少了 42.6%。封锁解除后，精子、睾丸和卵巢组织冷冻保存的水平恢复到封锁前的水平（95.2%）。仅对于卵母细胞冷冻保存，活动的恢复是部分的，其水平达到了封锁前的 56.8%。总共有 45 名患者（8.35%）在封锁期间失去了所有生育力保存的机会。