Chen Shuangqin, Huang Jianghua, Tang Xuan, Wang Ting, Zeng Yahua
The First Affiliated Hospital, Department of Neurology, Hengyang Medical School, University of South China, Hengyang, China.
The First Affiliated Hospital, Department of Rehabilitation, Hengyang Medical School, University of South China, Hengyang, China.
Front Surg. 2022 Feb 15;9:839523. doi: 10.3389/fsurg.2022.839523. eCollection 2022.
To explore the effects of transient electric acupuncture stimulation combined with rehabilitation training on hemorheology, neurological function and brain-derived neurotrophic factor (BDNF) in patients with cerebral infarction (CI).
A total of 90 patients with CI were admitted to our hospital from March 2019 to March 2021. According to the random number table method, 90 patients were divided into a control group (was treated with transient electrical acupuncture stimulation intervention treatment) and a therapy group (was treated with rehabilitation training on the basis of the control group), with 45 cases in each group. NIHSS score to detect neurological deficit; FMA score to detect motor function recovery; the clinical efficacy of the two groups of patients were compared; blood rheology analyzer to detect whole blood high shear viscosity, whole blood low shear viscosity, platelet aggregation rate and fibrinogen indicators; ELISA detects the content of BDNF in serum.
There was no significant difference in NIHSS score, FMA score, clinical efficacy, hemorheology index, and BDNF content between the two groups of patients before treatment ( > 0.05). After treatment, the NIHSS score, whole blood high shear visible, whole blood low shear visible, platelet aggregation rate and fibrinogen index of the two groups were lower than those before treatment, and the FMA score and BDNF content of the two groups were higher than those before treatment, and all the above indicators in the therapy group changed significantly compared with the control group ( < 0.05). After treatment, the clinical efficacy of the therapy group was better than that of the control group ( < 0.05).
The combination of transient electrical acupuncture stimulation and rehabilitation training can inhibit the blood flow index of patients with CI, improve the nerve function, increase the content of BDNF in the patient's serum, and restore the patient's nerve function.
探讨短暂电针刺激联合康复训练对脑梗死（CI）患者血液流变学、神经功能及脑源性神经营养因子（BDNF）的影响。
选取2019年3月至2021年3月我院收治的90例CI患者。根据随机数字表法，将90例患者分为对照组（采用短暂电针刺激干预治疗）和治疗组（在对照组基础上进行康复训练），每组45例。采用美国国立卫生研究院卒中量表（NIHSS）评分检测神经功能缺损；采用Fugl-Meyer评估量表（FMA）评分检测运动功能恢复情况；比较两组患者的临床疗效；采用血液流变分析仪检测全血高切黏度、全血低切黏度、血小板聚集率及纤维蛋白原指标；采用酶联免疫吸附测定（ELISA）法检测血清中BDNF的含量。
两组患者治疗前NIHSS评分、FMA评分、临床疗效、血液流变学指标及BDNF含量比较，差异无统计学意义（P>0.05）。治疗后，两组患者的NIHSS评分、全血高切黏度、全血低切黏度、血小板聚集率及纤维蛋白原指标均低于治疗前，FMA评分及BDNF含量均高于治疗前，且治疗组上述指标与对照组比较，差异有统计学意义（P<0.05）。治疗后，治疗组的临床疗效优于对照组（P<0.05）。
短暂电针刺激联合康复训练可抑制CI患者的血流指标，改善神经功能，提高患者血清中BDNF的含量，恢复患者神经功能。
