用G1（一种G蛋白偶联雌激素受体（GPER）激动剂）处理的MCF-7乳腺癌细胞的转录组数据。
Transcriptomic data of MCF-7 breast cancer cells treated with G1, a G-protein coupled estrogen receptor (GPER) agonist.
作者信息
Pal Uttariya, Sahu Ankur, Barah Pankaj, Limaye Anil Mukund
机构信息
Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati - 781039, Assam, India.
Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur 784028, Assam, India.
出版信息
Data Brief. 2022 Feb 13;41:107948. doi: 10.1016/j.dib.2022.107948. eCollection 2022 Apr.
Besides short-term non-genomic effects, the G-protein coupled estrogen receptor (GPER) also mediates long-term genomic effects of estrogen. The genomic effects of GPER activation are not completely understood. G1 is a selective GPER agonist, which is popularly used for addressing the effects of GPER activation. Here, we present transcriptomic (RNA-seq) data on MCF-7 cells treated with 100 nM, or 1 µM G1 for a period of 48 h. The data are available from GEO (accession number GSE188706).
除了短期非基因组效应外，G蛋白偶联雌激素受体（GPER）还介导雌激素的长期基因组效应。GPER激活的基因组效应尚未完全明确。G1是一种选择性GPER激动剂，常用于研究GPER激活的效应。在此，我们展示了用100 nM或1 µM G1处理MCF-7细胞48小时后的转录组（RNA测序）数据。这些数据可从基因表达综合数据库（GEO）获取（登录号GSE188706）。
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