一位 81 岁女性的隐匿性眼表病变。
Insidious ocular surface lesion in an 81-year-old woman.
机构信息
Department of Ophthalmology, Galway University Hospitals, Galway, Ireland.
Department of Ophthalmology, Galway University Hospitals, Galway, Ireland
出版信息
BMJ Case Rep. 2022 Mar 4;15(3):e248725. doi: 10.1136/bcr-2021-248725.
Ocular surface melanoma (OSM) is rare. An 81-year-old Caucasian woman presented with a 4-month history of right eye pain and reduced vision. Histopathological examination of the excisional biopsy identified invasive amelanotic melanoma of the conjunctiva expressing Melan A and SOX10. X-ray of chest, CT of liver and MRI of the brain and orbit did not identify macroscopic metastases. She was given adjuvant topical mitomycin-C 0.04% for four cycles of 2 weeks. Her vision improved and the cornea was clear at 6 months.
眼表面黑色素瘤（OSM）较为罕见。一位 81 岁的白人女性因右眼疼痛和视力下降 4 个月就诊。切除活检的组织病理学检查显示，结膜侵袭性无黑色素瘤表达 Melan A 和 SOX10。胸部 X 线、肝脏 CT 及脑和眼眶 MRI 均未发现肉眼转移。她接受了四个周期（每个周期 2 周）的局部辅助性丝裂霉素 C 0.04%治疗。她的视力在 6 个月时得到改善，角膜清晰。
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