Department of General Surgery, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, Turkey.
Department of General Surgery, Istanbul Medeniyet University, Göztepe Training and Research Hospital, Istanbul, Turkey.
Prague Med Rep. 2022;123(1):20-26. doi: 10.14712/23362936.2022.2.
Upper gastrointestinal subepithelial tumours (SETs) are generally asymptomatic and clinically insignificant and have malign, borderline and benign variants. In advanced endoscopic procedures, histopathological diagnosis and endoscopic resection are possible and feasible. In this study, we examined our approach to upper gastrointestinal subepithelial tumours and our clinical results. Adult patients who applied to Surgical Endoscopy unit between January 2014 and January 2015 were included in the study. The patients' files and final histopathological diagnoses were recorded and analysed retrospectively for this single-center study. SET lesion lower than 30 mm and the lesion whose endoscopic submucosal dissection attemption was included in the study. The total of 8 patients were four female (50%) and four male (50%), aged 31-66 years (median, 53 years). The tumoral lesions were located 4 (50%) patients in esophagus, 3 (37.5%) patients in stomach and one (12.5%) patient in duodenum and their diameter ranged from 5 to 30 mm (median, 14 mm). Post-interventional no complications or abdominal symptoms were encountered. Also, in early follow-ups for six months, no recurrence was observed. Our experiences together with literature reported here, indicated endoscopic resection is a safe and effective method of treatment for most patients with upper gastrointestinal SETs.
上消化道黏膜下肿瘤(SETs)通常无症状,临床上意义不大,且具有恶性、交界性和良性等多种类型。在先进的内镜治疗中,可进行组织病理学诊断和内镜下切除。本研究旨在探讨上消化道黏膜下肿瘤的治疗方法及临床效果。
回顾性分析 2014 年 1 月至 2015 年 1 月期间在外科内镜诊疗中心就诊的成年患者资料,纳入符合条件的患者,记录其临床资料及最终组织病理学诊断。本研究纳入直径<30mm 的上消化道 SET 病变,且尝试内镜黏膜下剥离术的患者。
共纳入 8 例患者,其中女 4 例(50%),男 4 例(50%),年龄 31-66 岁,中位年龄 53 岁。肿瘤位于食管 4 例(50%),胃 3 例(37.5%),十二指肠 1 例(12.5%),直径 5-30mm,中位直径 14mm。术后无并发症或腹部症状,6 个月的早期随访中未观察到复发。
本研究结果与文献报道的经验一致,提示内镜下切除是治疗大多数上消化道 SETs 患者的安全有效的方法。