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非抗反流机器人辅助腹腔镜输尿管再植术治疗输尿管梗阻的长期疗效。

Long-Term Outcome of Non-antireflux Robotic-Assisted Robot-Assisted Laparoscopic Ureter Reimplantation in Ureteral Obstruction.

机构信息

Department of Urology, University Hospital Basel, Basel, Switzerland.

Medical Faculty, University of Basel, Basel, Switzerland.

出版信息

J Endourol. 2022 Sep;36(9):1183-1191. doi: 10.1089/end.2022.0055.

Abstract

Although robot-assisted laparoscopic ureter reimplantation (RALUR) is a recognized alternative to open and laparoscopic ureter reimplantation in treating distal ureteral obstruction, there are limited data on long-term efficacy and safety outcomes of non-antireflux RALUR. We assessed patients undergoing RALUR, evaluating operative, functional, and safety determinants. All consecutive patients undergoing non-antireflux RALUR between April 2015 and January 2020 were included in this retrospective cohort study. The primary outcome endpoint was recurrent distal ureteral obstruction. Mean follow-up was 41.3 months (95% confidence interval, 33.3-49.2; range 2-82). Among the 26 included patients, none developed recurrent distal ureteral obstruction. Kidney function in terms of serum creatinine level (72.0 μmol/L 71.0 μmol/L,  = 0.988) and glomerular filtration rate (92.0 mL/min 91.0 mL/min,  = 0.831) was stable between the preoperative period and the last follow-up. Renal pelvis dilatation decreased significantly postoperatively, from grade 2 to grade 0 ( < 0.001). Most patients (73.1%) remained free from any clinical symptoms of reflux during the follow-up. No recurring urinary tract infections were reported. The rate of postoperative complications (Clavien-Dindo grade ≥II) was 23.1%. All complications resolved without sequelae. Non-antireflux RALUR appears to be safe and effective in the management of distal ureteral obstruction. There was no recurrent ureteral obstruction after RALUR in our cohort during a mean follow-up of more than 3 years. Non-antireflux reimplantation did not seem to have any notable impact on renal function during the follow-up period.

摘要

虽然机器人辅助腹腔镜输尿管再植术(RALUR)是治疗远端输尿管梗阻的公认替代开放和腹腔镜输尿管再植术,但关于非抗反流 RALUR 的长期疗效和安全性结果的数据有限。我们评估了接受 RALUR 的患者,评估了手术、功能和安全性决定因素。 本回顾性队列研究纳入了 2015 年 4 月至 2020 年 1 月期间接受非抗反流 RALUR 的所有连续患者。主要结局终点是复发性远端输尿管梗阻。 中位随访时间为 41.3 个月(95%置信区间,33.3-49.2;范围 2-82)。26 例纳入患者均未发生远端输尿管再梗阻。 血清肌酐水平(72.0 μmol/L vs. 71.0 μmol/L,=0.988)和肾小球滤过率(92.0 mL/min vs. 91.0 mL/min,=0.831)在术前和最后一次随访期间稳定。 术后肾盂扩张显著减少,从 2 级降至 0 级(<0.001)。大多数患者(73.1%)在随访期间无任何反流临床症状。无复发性尿路感染报告。术后并发症(Clavien-Dindo 分级≥II)发生率为 23.1%。所有并发症均无后遗症解决。 非抗反流 RALUR 在治疗远端输尿管梗阻方面似乎是安全有效的。在超过 3 年的中位随访期间,我们的队列中 RALUR 后没有复发性输尿管梗阻。在随访期间,非抗反流再植入似乎对肾功能没有明显影响。

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