Department for Companion Animals and Horses, Clinical Unit of Small Animals Internal Medicine, Dermatology, University of Veterinary Medicine, Vienna, Austria.
Institute of Pathology, Department for Pathobiology, University of Veterinary Medicine, Vienna, Austria.
J Am Vet Med Assoc. 2022 Mar 8;260(10):1-4. doi: 10.2460/javma.21.03.0149.
A 9-year-old spayed female Maine Coon cat was presented at the University of Veterinary Medicine Vienna for further investigation of chronic nonpruritic bilateral ear disease and unilateral Horner syndrome.
Physical examination and otoscopy findings included right sided Horner syndrome, a right head tilt of approximately 20° and a small pink nodule in the right and several smaller nodules in the left proximal horizontal external ear canal. Computed tomography and magnetic resonance imaging revealed soft tissue opacity material in both middle ear cavities, the caudal portion of the nasal cavity, the left nasopharyngeal meatus and the right frontal sinus. Via videootoscopy, 2 multilobular and several flat nodules were detected in the proximal right horizontal external ear canal and in the left tympanic bulla, respectively. Histopathological examination confirmed the diagnosis of cholesterol granulomas.
All otic cholesterol granulomas (CGs) were removed via video-otoscopy (VO), and topical treatment was initiated in addition to oral prednisolone. After the histopathological confirmation, negative microbial cultures from the middle ear cavities, and the remission of the symptoms by the first recheck, topical, and systemic treatment were discontinued. A follow-up 6 months later, did not reveal any recurrence of the CGs.
To our knowledge, this is the first case of bilateral CGs diagnosed with a combination of CT, MRI, VO, and histopathology and removed minimal invasively via VO, without a need for ventral bulla osteotomy, which led to complete remission of all signs and no relapse until the follow up 6 months later.
一只 9 岁已绝育的雌性缅因库恩猫因慢性非瘙痒性双侧耳部疾病和单侧霍纳综合征到维也纳兽医大学进一步检查。
体格检查和耳镜检查结果包括右侧霍纳综合征、约 20°的右侧头部倾斜以及右侧一个小的粉红色小结节和左侧外耳道口近端水平部的几个较小结节。计算机断层扫描和磁共振成像显示两侧中耳腔、鼻腔尾部、左侧咽鼓管和右侧额窦均有软组织不透明物质。通过视频耳镜检查,在右侧外耳道口近端和左侧鼓室分别发现 2 个多叶状和几个扁平结节。组织病理学检查证实了胆固醇肉芽肿的诊断。
所有耳部胆固醇肉芽肿(CG)均通过视频耳镜检查(VO)切除,除了口服泼尼松龙外,还开始了局部治疗。在组织病理学证实后,中耳腔的微生物培养均为阴性,症状在第一次复查时得到缓解,停止了局部和全身治疗。6 个月后的随访没有发现 CG 复发。
据我们所知,这是首例通过 CT、MRI、VO 和组织病理学相结合诊断双侧 CG,并通过 VO 微创切除,无需进行腹侧鼓室切开术的病例,这导致所有症状完全缓解,且在 6 个月的随访中没有复发。