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纯素食饮食与1型糖尿病患者的血糖控制:一例报告

Fruitarian Diet and Blood Glucose Control in Type 1 Diabetes: A Case Report.

作者信息

Vetrani Claudia, Bozzetto Lutgarda, Della Pepa Giuseppe, Rivellese Angela Albarosa, Annuzzi Giovanni

机构信息

Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy.

出版信息

Front Nutr. 2022 Feb 22;9:752832. doi: 10.3389/fnut.2022.752832. eCollection 2022.

Abstract

Diet is a key determinant of blood glucose control in individuals with type 1 diabetes. Although dietary education is part of their clinical follow-up, many patients show a propensity to self-treatment, adopting dietary changes, often extreme, that do not consider the overall impact on health. Here, we describe the case of a patient with type 1 diabetes who switched to a fruitarian diet because of ideological beliefs. A 25-year-old man with type 1 diabetes on an insulin pump and continuous glucose monitoring on optimal blood glucose control (HbA1c 6.5%, 48 mmol/mol; glucose time-in-range 70-180 mg/dl, TIR, 90%; coefficient of variation, CV, 36%) switched to a fruitarian diet because of ideological beliefs. After 3 months on this diet, blood glucose control was still optimal (TIR 88%, CV 33%), while plasma triglycerides and liver enzymes were above normal values. After 3 more months, blood glucose control had worsened (TIR 72%, CV 37%), plasma triglyceride and liver enzymes were within normal values, and hyperkalemia was detected. In this case report, a strict fruitarian diet was associated with early negative changes in some biochemical parameters, also in presence of optimal blood glucose control. Dietary counseling remains essential in the follow-up of patients with type 1 diabetes to ensure personalized medical nutrition therapy and monitor dietary changes that may affect health but with no major impact on blood glucose control.

摘要

饮食是1型糖尿病患者血糖控制的关键决定因素。尽管饮食教育是他们临床随访的一部分,但许多患者表现出自我治疗的倾向,采取饮食改变,通常是极端的,而不考虑对健康的整体影响。在此,我们描述了一名1型糖尿病患者因意识形态信仰而改为纯水果饮食的病例。一名25岁的1型糖尿病男性,使用胰岛素泵并进行持续血糖监测,血糖控制良好(糖化血红蛋白HbA1c 6.5%,48 mmol/mol;血糖在目标范围内的时间TIR为70 - 180 mg/dl,TIR为90%;变异系数CV为36%),因意识形态信仰改为纯水果饮食。采用这种饮食3个月后,血糖控制仍然良好(TIR 88%,CV 33%),而血浆甘油三酯和肝酶高于正常值。再过3个月后,血糖控制恶化(TIR 72%,CV 37%),血浆甘油三酯和肝酶在正常范围内,且检测到高钾血症。在本病例报告中,严格的纯水果饮食与一些生化参数的早期负面变化相关,即使在血糖控制良好的情况下也是如此。饮食咨询在1型糖尿病患者的随访中仍然至关重要,以确保个性化的医学营养治疗,并监测可能影响健康但对血糖控制无重大影响的饮食变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8bf/8904176/391c0ad9c349/fnut-09-752832-g0001.jpg

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