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本文引用的文献

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Is there a role for treatment-oriented surgery in liver metastases from gastric cancer?以治疗为导向的手术在胃癌肝转移中是否有作用?
World J Clin Oncol. 2020 Jul 24;11(7):477-494. doi: 10.5306/wjco.v11.i7.477.
2
Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study.全球、区域和国家癌症发病率、死亡率、生命损失年数、失能生存年数以及 29 种癌症组别的伤残调整生命年数:1990 至 2017 年全球疾病负担研究的系统分析。
JAMA Oncol. 2019 Dec 1;5(12):1749-1768. doi: 10.1001/jamaoncol.2019.2996.
3
The Role of Surgical Resection for Stage IV Gastric Cancer With Synchronous Hepatic Metastasis.手术切除在伴有同步肝转移的IV期胃癌中的作用
J Surg Res. 2018 Dec;232:422-429. doi: 10.1016/j.jss.2018.06.067. Epub 2018 Jul 21.
4
Outcomes of 1,639 hepatectomies for non-colorectal non-neuroendocrine liver metastases: a multicenter analysis.1639 例非结直肠非神经内分泌肝转移瘤肝切除术的结果:一项多中心分析。
J Hepatobiliary Pancreat Sci. 2018 Nov;25(11):465-475. doi: 10.1002/jhbp.587. Epub 2018 Nov 20.
5
Surgical treatment of hepatic metastases from gastric cancer.胃癌肝转移的外科治疗
Updates Surg. 2018 Jun;70(2):273-278. doi: 10.1007/s13304-018-0536-2. Epub 2018 May 29.
6
Surgical resection for hepatic metastasis from gastric cancer: a multi- institution study.胃癌肝转移的手术切除:一项多机构研究。
Oncotarget. 2017 Mar 30;8(41):71147-71153. doi: 10.18632/oncotarget.16705. eCollection 2017 Sep 19.
7
The long-term survival of stage IV gastric cancer patients with conversion therapy.IV 期胃癌患者经转化治疗后的长期生存。
Gastric Cancer. 2018 Mar;21(2):315-323. doi: 10.1007/s10120-017-0738-1. Epub 2017 Jun 14.
8
Surgical resection of hepatic metastases from gastric cancer: outcomes from national series in England.胃癌肝转移灶的手术切除:英格兰全国系列研究的结果
Gastric Cancer. 2017 Mar;20(2):379-386. doi: 10.1007/s10120-016-0604-6. Epub 2016 Mar 3.
9
Is conversion therapy possible in stage IV gastric cancer: the proposal of new biological categories of classification.IV期胃癌是否可行转化治疗:新的生物学分类范畴建议
Gastric Cancer. 2016 Apr;19(2):329-338. doi: 10.1007/s10120-015-0575-z. Epub 2015 Dec 7.
10
Surgical treatment of liver metastasis of gastric cancer: a retrospective multicenter cohort study (KSCC1302).胃癌肝转移的外科治疗:一项回顾性多中心队列研究(KSCC1302)
Gastric Cancer. 2016 Jul;19(3):968-76. doi: 10.1007/s10120-015-0530-z. Epub 2015 Aug 11.

胃癌肝转移新治疗算法的提议: upfront手术还是转化手术?

Proposal of new treatment algorithm for gastric cancer liver metastases: Up-front surgery or conversion surgery?

作者信息

Takemura Nobuyuki, Saiura Akio, Ito Hiromichi, Ito Kyoji, Inagaki Fuyuki, Mihara Fuminori, Yagi Shusuke, Enomoto Naoki, Nohara Kyoko, Inoue Yosuke, Takahashi Yu, Yamada Kazuhiko, Kokudo Norihiro

机构信息

Department of Surgery, Hepato-Biliary Pancreatic Surgery Division, National Center for Global Health and Medicine, Tokyo, Japan.

Department of Hepatobiliary Pancreatic Surgery, Juntendo University Hospital, Tokyo, Japan.

出版信息

Glob Health Med. 2022 Feb 28;4(1):57-60. doi: 10.35772/ghm.2021.01102.

DOI:10.35772/ghm.2021.01102
PMID:35291203
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8884038/
Abstract

Hepatectomy for gastric cancer liver metastases (GCLM) has a 5-year survival rate of 9-42%; however, indications for hepatectomy remain unclear. Many researchers have reported prognostic factors for GCLM after hepatectomy, but surgical indications vary according to the literature. Furthermore, the indication for optimal candidates for neoadjuvant chemotherapy and intensive chemotherapy is also unclear. To understand the indications for surgery and chemotherapy intended for hepatectomy for GCLM, a new treatment algorithm was created based on previously reported evidence from the viewpoint of hepatic surgeons.

摘要

胃癌肝转移(GCLM)的肝切除术5年生存率为9% - 42%;然而,肝切除术的指征仍不明确。许多研究人员报告了肝切除术后GCLM的预后因素,但根据文献,手术指征各不相同。此外,新辅助化疗和强化化疗的最佳候选者的指征也不明确。为了了解GCLM肝切除术的手术和化疗指征,从肝脏外科医生的角度出发,基于先前报道的证据创建了一种新的治疗算法。