使用患者定制的近轴眼模型预测人工晶状体眼的屈光状态。
Predictability of pseudophakic refraction using patient-customized paraxial eye models.
机构信息
From the Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida (Chang, Cabot, Heilman, Meza, Ruggeri, Ho, Yoo, Parel, Manns); Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida (Chang, Heilman, Meza, Ruggeri, Ho, Yoo, Parel, Manns); Anne Bates Leach Eye Hospital, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida (Cabot, Yoo, Parel); Brien Holden Vision Institute Limited, Sydney, New South Wales, Australia (Ho, Parel).
出版信息
J Cataract Refract Surg. 2022 Sep 1;48(9):1016-1022. doi: 10.1097/j.jcrs.0000000000000934.
PURPOSE
To determine whether patient-customized paraxial eye models that do not rely on exact ray tracing and do not consider aberrations can accurately predict pseudophakic refraction.
SETTING
Bascom Palmer Eye Institute, Miami, Florida.
DESIGN
Prospective study.
METHODS
Cataract surgery patients with and without a history of refractive surgery were included. Manifest refraction, corneal biometry, and extended-depth optical coherence tomography (OCT) imaging were performed at least 1 month postoperatively. Corneal and OCT biometry were used to create paraxial eye models. The pseudophakic refraction simulated using the eye model was compared with measured refraction to calculate prediction error.
RESULTS
49 eyes of 33 patients were analyzed, of which 12 eyes from 9 patients had previous refractive surgery. In eyes without a history of refractive surgery, the mean prediction error was 0.08 ± 0.33 diopters (D), ranging from -0.56 to 0.79 D, and the mean absolute error was 0.27 ± 0.21 D. 31 eyes were within ±0.5 D, and 36 eyes were within ±0.75 D. In eyes with previous refractive surgery, the mean prediction error was -0.44 ± 0.58 D, ranging from -1.42 to 0.32 D, and the mean absolute error was 0.56 ± 0.46 D. 7 of 12 eyes were within ±0.5 D, 8 within ±0.75 D, and 10 within ±1 D. All eyes were within ±1.5 D.
CONCLUSIONS
Accurate calculation of refraction in postcataract surgery patients can be performed using paraxial optics. Measurement uncertainties in ocular biometry are a primary source of residual prediction error.
目的
确定不依赖于精确光线追踪且不考虑像差的患者定制离轴眼模型是否可以准确预测白内障术后屈光。
设置
迈阿密巴斯科姆帕尔默眼科研究所，佛罗里达州。
设计
前瞻性研究。
方法
纳入白内障手术患者，无论是否有屈光手术史。术后至少 1 个月进行主观验光、角膜生物测量和扩展景深光学相干断层扫描（OCT）成像。使用角膜和 OCT 生物测量来创建离轴眼模型。使用眼模型模拟的白内障术后屈光与实际测量的屈光进行比较，以计算预测误差。
结果
分析了 33 名患者的 49 只眼，其中 9 名患者的 12 只眼有既往屈光手术史。在无屈光手术史的眼中，平均预测误差为 0.08 ± 0.33 屈光度（D），范围为-0.56 至 0.79 D，平均绝对误差为 0.27 ± 0.21 D。31 只眼在±0.5 D 以内，36 只眼在±0.75 D 以内。在有既往屈光手术史的眼中，平均预测误差为-0.44 ± 0.58 D，范围为-1.42 至 0.32 D，平均绝对误差为 0.56 ± 0.46 D。12 只眼中的 7 只眼在±0.5 D 以内，8 只眼在±0.75 D 以内，10 只眼在±1 D 以内。所有眼睛均在±1.5 D 以内。
结论
在白内障术后患者中，可以使用离轴光学准确计算屈光。眼生物测量的测量不确定度是残余预测误差的主要来源。
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