Djønne B K
Acta Vet Scand. 1986;27(1):115-23. doi: 10.1186/BF03548564.
Three hundred and fifteen E. coli strains isolated from the intestine of piglets were examined for K-antigens 88 and 99, enterotoxin production and colicin resistance. Of these strains 308 belonged to one of 3 following different groups: Group 1: 0149, K88, producing heat-labile (LT) and heat-stable (ST) enterotoxins, group 2: 064, K99, producing ST, and group 3: variable O-antigens, no K-antigens or enterotoxin production. Almost 100 % of the E. coli strains were found to be resistant to colicins E, E, Ia, H and D+X. Resistance to colicins E, B+M, V and K+X were found in 91.7 %, 43.8 %, 49.8 % and 62.2 % respectively. E. coli strains in group 1 were always (resistant to colicin E, while about 87 % of the other strains were resistant to this colicin. E. coli strains in group 2 were more often resistant to colicin B+M, V and K+X (65 %, 94 %, 83 %) than strains in group 1 (37 %, 24 %, 64 %) and strains in group 3 (37 %, 52 %, 46 %). E. coli strains in group 2 showed a high degree of multiresistance, 45.1 % of the strains being resistant to all of the 9 colicins. About 10 % of the other strains were resistant to all of the 9 colicins. E. coli strains harbouring the enteropathogenicity factors K99 antigen and ST production, showed a higher degree of colicin resistance than both the E. coli strains with K88 antigen and ST and LT production, and the E. coli strains lacking enteropathogenicity factors.
对从仔猪肠道分离出的315株大肠杆菌进行了K抗原88和99、肠毒素产生及对大肠杆菌素抗性的检测。这些菌株中，308株属于以下3个不同组之一：第1组：O149，K88，产生不耐热（LT）和耐热（ST）肠毒素；第2组：O64，K99，产生ST；第3组：O抗原可变，无K抗原或不产生肠毒素。几乎100%的大肠杆菌菌株对大肠杆菌素E、E、Ia、H和D+X耐药。对大肠杆菌素E、B+M、V和K+X的耐药率分别为91.7%、43.8%、49.8%和62.2%。第1组的大肠杆菌菌株总是对大肠杆菌素E耐药，而其他菌株中约87%对该大肠杆菌素耐药。第2组的大肠杆菌菌株比第1组（37%、24%、64%）和第3组（37%、52%、46%）的菌株更常对大肠杆菌素B+M、V和K+X耐药（65%、94%、83%）。第2组的大肠杆菌菌株表现出高度多重耐药性，45.1%的菌株对所有9种大肠杆菌素耐药。其他菌株中约10%对所有9种大肠杆菌素耐药。携带K99抗原和ST产生等肠道致病因子的大肠杆菌菌株，比同时携带K88抗原以及ST和LT产生的大肠杆菌菌株，以及缺乏肠道致病因子的大肠杆菌菌株表现出更高程度的对大肠杆菌素的耐药性。
