Department of Anesthesiology and Pain Medicine, 108 Military Central Hospital, No.1 Tran Hung Dao Street, Hai Ba Trung District, Ha Noi City, 100000, Vietnam.
Department of Thoracic surgery, 108 Military Central Hospital, Hanoi, Vietnam.
BMC Anesthesiol. 2022 Mar 18;22(1):73. doi: 10.1186/s12871-022-01610-y.
Tracheal resection and reconstruction are the most effective treatments for tracheal stenosis, but the difficulties are surgery and maintaining ventilation performed on the patient's same airway. High-flow oxygen has begun to be applied to prolong the apnoea time in the tracheal anastomosis period for tracheal resection and reconstruction. This study aims to evaluate the effectiveness of apneic conditions with high-flow oxygen as the sole method of gas exchange during anastomosis construction.
A prospective study was performed on 16 patients with tracheal stenosis, with ages ranging from 19 to 70, who underwent tracheal resection and reconstruction from April 2019 to August 2020 in 108 Military Central Hospital. During the anastomosis phase using high flow oxygen of 35-40 l.min-1 delivered across the open tracheal with an endotracheal tube (ETT) at the glottis in apnoeic conditions.
The mean (SD) apnoea time was 20.91 (2.53) mins. Mean (SD) time anastomosis was 22.9 (2.41) mins. The saturation of oxygen was stable during all procedures at 98-100%. Arterial blood gas analysis showed mean (SD) was hypercapnia and acidosis acute respiratory after 10 mins of apnoea and 20 mins apnoea respectively. However, after 15 mins of ventilation, the parameters are ultimately returned to normal. All 16 patients were extubated early and safely at the end of the operation. There were no complications, such as bleeding, hemothorax, pneumothorax, or barotrauma.
High-flow oxygen across the open tracheal under apnoeic conditions can provide a satisfactory gas exchange to allow tubeless anesthesia for tracheal resection and reconstruction.
气管切除术和重建术是治疗气管狭窄最有效的方法,但手术和维持患者同一气道的通气都存在困难。高流量吸氧已开始应用于延长气管切除和重建吻合期的无通气时间。本研究旨在评估高流量氧气作为唯一的气体交换方法在吻合口构建期间无通气条件下的有效性。
2019 年 4 月至 2020 年 8 月,在 108 军中央医院对 16 例年龄在 19 至 70 岁之间的气管狭窄患者进行了前瞻性研究,这些患者接受了气管切除术和重建术。在无通气条件下,通过在声门处用气管内管(ETT)将 35-40l.min-1 的高流量氧气输送到开放的气管中,进行吻合阶段。
平均(SD)无通气时间为 20.91(2.53)分钟。平均(SD)吻合时间为 22.9(2.41)分钟。所有手术过程中的氧饱和度均稳定在 98-100%之间。动脉血气分析显示,无通气 10 分钟和 20 分钟后分别出现急性呼吸性高碳酸血症和酸中毒。然而,通气 15 分钟后,所有参数最终恢复正常。所有 16 例患者在手术结束时均早期、安全地拔管。无出血、血胸、气胸或气压伤等并发症。
在无通气条件下,通过开放的气管输送高流量氧气可以提供令人满意的气体交换,从而实现气管切除和重建术的无管麻醉。