双侧岩下窦联合加压素刺激采样在儿科库欣病中的诊断效能。
Diagnostic Power of Bilateral Inferior Petrosal Sinus Sampling with Desmopressin in Paediatric Cushing’s Disease.
机构信息
Hospital Nacional Dos de Mayo, Lima, Peru
ADIECS Association for the Development of Student Research in Health Sciences, Universidad Nacional Mayor de San Marcos, Lima, Peru
出版信息
J Clin Res Pediatr Endocrinol. 2022 Aug 25;14(3):334-338. doi: 10.4274/jcrpe.galenos.2022.2022-12-9. Epub 2022 Mar 21.
Abstract
OBJECTIVE
The aim of this study was to evaluate the diagnostic accuracy of bilateral inferior petrosal sinus sampling (BIPSS) with desmopressin for pediatric Cushing’s disease (CD).
METHODS
We reviewed studies performed in children that evaluated the accuracy of BIPSS with desmopressin.
RESULTS
All included studies were case series of children with adrenocorticotropin hormone (ACTH)-dependent Cushing’s syndrome. The overall accuracy of BIPSS before stimulation was 84.1% (37/44), and after stimulation it was 92.3% (36/39). The overall lateralizing accuracy of BIPSS was 50.0%.
CONCLUSION
Considering that available evidence is limited, it appears that BIPSS with desmopressin stimulation is accurate for the diagnosis of pediatric CD, but its lateralizing accuracy is probably not suitable for pediatric clinical practice.
摘要
目的
本研究旨在评估加压素刺激双侧岩下窦采样（BIPSS）对儿童库欣病（CD）的诊断准确性。
方法
我们回顾了评估加压素刺激 BIPSS 准确性的儿童研究。
结果
所有纳入的研究均为促肾上腺皮质激素（ACTH）依赖性库欣综合征患儿的病例系列研究。刺激前 BIPSS 的总体准确性为 84.1%（37/44），刺激后为 92.3%（36/39）。BIPSS 的总体定位准确性为 50.0%。
结论
考虑到现有证据有限，加压素刺激 BIPSS 似乎可准确诊断儿童 CD，但定位准确性可能不适合儿科临床实践。
相似文献
1
Diagnostic Power of Bilateral Inferior Petrosal Sinus Sampling with Desmopressin in Paediatric Cushing’s Disease.
J Clin Res Pediatr Endocrinol. 2022 Aug 25;14(3):334-338. doi: 10.4274/jcrpe.galenos.2022.2022-12-9. Epub 2022 Mar 21.
2
A case series of bilateral inferior petrosal sinus sampling with desmopressin in evaluation of ACTH-dependent Cushing's syndrome in Iran.
Hormones (Athens). 2021 Jun;20(2):299-304. doi: 10.1007/s42000-020-00240-8. Epub 2020 Sep 15.
3
Enhancing Cushing's disease diagnosis: exploring the impact of desmopressin on ACTH gradient during BIPSS.
Front Endocrinol (Lausanne). 2023 Aug 3;14:1224001. doi: 10.3389/fendo.2023.1224001. eCollection 2023.
4
The effects of sampling lateralization on bilateral inferior petrosal sinus sampling and desmopressin stimulation test for pediatric Cushing's disease.
Endocrine. 2019 Mar;63(3):582-591. doi: 10.1007/s12020-018-1779-x. Epub 2018 Oct 11.
5
The application of a combined stimulation with CRH and desmopressin during bilateral inferior petrosal sinus sampling in patients with Cushing's syndrome.
Clin Endocrinol (Oxf). 2000 Mar;52(3):355-61. doi: 10.1046/j.1365-2265.2000.00943.x.
6
The application of the combined corticotropin-releasing hormone plus desmopressin stimulation during petrosal sinus sampling is both sensitive and specific in differentiating patients with Cushing's disease from patients with the occult ectopic adrenocorticotropin syndrome.
J Clin Endocrinol Metab. 2007 Jun;92(6):2080-6. doi: 10.1210/jc.2006-2691. Epub 2007 Mar 13.
7
Bilateral inferior petrosal sinus sampling: validity, diagnostic accuracy in lateralization of pituitary microadenoma, and treatment in eleven patients with Cushing's syndrome - a single-center retrospective cohort study.
BMC Endocr Disord. 2023 Oct 23;23(1):232. doi: 10.1186/s12902-023-01495-z.
8
Diagnostic accuracy of bilateral inferior petrosal sinus sampling using desmopressin or corticotropic- releasing hormone in ACTH-dependent Cushing's syndrome: A systematic review and meta-analysis.
Rev Endocr Metab Disord. 2022 Oct;23(5):881-892. doi: 10.1007/s11154-022-09723-y. Epub 2022 Apr 28.
9
High accuracy of bilateral and simultaneous petrosal sinus sampling with desmopressin for the differential diagnosis of pediatric ACTH-dependent Cushing's syndrome.
Pituitary. 2020 Oct;23(5):507-514. doi: 10.1007/s11102-020-01051-1.
10
Diagnostic Accuracy of the Desmopressin Stimulation Test in the Comprehensive Assessment of ACTH-Dependent Cushing's Syndrome: A Comparative Analysis with BIPSS and TSS.
Endocr Res. 2024 Aug-Nov;49(4):232-242. doi: 10.1080/07435800.2024.2381720. Epub 2024 Jul 20.
引用本文的文献
1
Cushing syndrome in paediatric population: who and how to screen.
J Endocrinol Invest. 2025 Apr;48(Suppl 1):7-19. doi: 10.1007/s40618-024-02452-w. Epub 2024 Sep 30.
2
Consensus guideline for the diagnosis and management of pituitary adenomas in childhood and adolescence: Part 2, specific diseases.
Nat Rev Endocrinol. 2024 May;20(5):290-309. doi: 10.1038/s41574-023-00949-7. Epub 2024 Feb 9.
本文引用的文献
1
Utility of bilateral inferior petrosal sinus sampling for diagnosis and lateralization of Cushing's disease in the pediatric population: case series and review of the literature.
J Endocrinol Invest. 2022 Mar;45(3):617-627. doi: 10.1007/s40618-021-01680-8. Epub 2021 Oct 15.
2
The Effects of Sampling Lateralization on Bilateral Inferior Petrosal Sinus Sampling for Pediatric Cushing's Disease-A Single Endocrinology Centre Experience and Review of the Literature.
Front Endocrinol (Lausanne). 2021 Apr 19;12:650967. doi: 10.3389/fendo.2021.650967. eCollection 2021.
3
Paediatric Cushing's disease: Epidemiology, pathogenesis, clinical management and outcome.
Rev Endocr Metab Disord. 2021 Dec;22(4):817-835. doi: 10.1007/s11154-021-09626-4. Epub 2021 Jan 30.
4
Evaluation and Treatment of Patients With Hypercortisolism: A Review.
JAMA Surg. 2020 Dec 1;155(12):1152-1159. doi: 10.1001/jamasurg.2020.3280.
5
High accuracy of bilateral and simultaneous petrosal sinus sampling with desmopressin for the differential diagnosis of pediatric ACTH-dependent Cushing's syndrome.
Pituitary. 2020 Oct;23(5):507-514. doi: 10.1007/s11102-020-01051-1.
6
Cushing's syndrome: Overview of clinical presentation, diagnostic tools and complications.
Best Pract Res Clin Endocrinol Metab. 2020 Mar;34(2):101380. doi: 10.1016/j.beem.2020.101380. Epub 2020 Jan 30.
7
Diagnostic accuracy of Bilateral Inferior Petrosal Sinus Sampling: The Experience of a Tertiary Centre.
Exp Clin Endocrinol Diabetes. 2021 Feb;129(2):126-130. doi: 10.1055/a-0981-5973. Epub 2019 Aug 19.
8
The effects of sampling lateralization on bilateral inferior petrosal sinus sampling and desmopressin stimulation test for pediatric Cushing's disease.
Endocrine. 2019 Mar;63(3):582-591. doi: 10.1007/s12020-018-1779-x. Epub 2018 Oct 11.
9
Tumour lateralization in Cushing's disease by inferior petrosal sinus sampling with desmopressin.
Clin Endocrinol (Oxf). 2018 Feb;88(2):251-257. doi: 10.1111/cen.13505. Epub 2017 Nov 27.
10
Bilateral inferior petrosal sinus sampling: experience in 327 patients.
J Neurointerv Surg. 2017 Feb;9(2):196-199. doi: 10.1136/neurintsurg-2015-012164. Epub 2016 Feb 15.
Zotero 插件