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一种诱导躯干肌肉损伤的离心等速运动方案的可行性:一项初步研究。

Feasability of An Eccentric Isokinetic Protocol to Induce Trunk Muscle Damage: A Pilot Study.

作者信息

Engel Tilman, Schraplau Anne, Wochatz Monique, Kopinski Stephan, Sonnenburg Dominik, Schomoeller Anne, Risch Lucie, Kaplick Hannes, Mayer Frank

机构信息

University Outpatient Clinic, Sports Medicine & Sports Orthopaedics, University of Potsdam, Potsdam, Germany.

出版信息

Sports Med Int Open. 2022 Mar 19;6(1):E9-E17. doi: 10.1055/a-1757-6724. eCollection 2022 Jan.

Abstract

Eccentric exercise is discussed as a treatment option for clinical populations, but specific responses in terms of muscle damage and systemic inflammation after repeated loading of large muscle groups have not been conclusively characterized. Therefore, this study tested the feasibility of an isokinetic protocol for repeated maximum eccentric loading of the trunk muscles. Nine asymptomatic participants (5 f/4 m; 34±6 yrs; 175±13 cm; 76±17 kg) performed three isokinetic 2-minute all-out trunk strength tests (1x concentric (CON), 2x eccentric (ECC1, ECC2), 2 weeks apart; flexion/extension, 60°/s, ROM 55°). Outcomes were peak torque, torque decline, total work, and indicators of muscle damage and inflammation (over 168 h). Statistics were done using the Friedman test (Dunn's post-test). For ECC1 and ECC2, peak torque and total work were increased and torque decline reduced compared to CON. Repeated ECC bouts yielded unaltered torque and work outcomes. Muscle damage markers were highest after ECC1 (soreness 48 h, creatine kinase 72 h; p<0.05). Their overall responses (area under the curve) were abolished post-ECC2 compared to post-ECC1 (p<0.05). Interleukin-6 was higher post-ECC1 than CON, and attenuated post-ECC2 (p>0.05). Interleukin-10 and tumor necrosis factor-α were not detectable. All markers showed high inter-individual variability. The protocol was feasible to induce muscle damage indicators after exercising a large muscle group, but the pilot results indicated only weak systemic inflammatory responses in asymptomatic adults.

摘要

离心运动作为临床人群的一种治疗选择进行了讨论,但在大肌肉群反复负荷后,肌肉损伤和全身炎症方面的具体反应尚未得到最终明确。因此,本研究测试了一种等速方案用于躯干肌肉反复最大离心负荷的可行性。九名无症状参与者(5名女性/4名男性;34±6岁;175±13厘米;76±17千克)进行了三次等速2分钟全力躯干力量测试(1次向心收缩(CON),2次离心收缩(ECC1、ECC2),间隔2周;屈伸,60°/秒,活动范围55°)。结果指标为峰值扭矩、扭矩下降、总功以及肌肉损伤和炎症指标(超过168小时)。使用Friedman检验(Dunn事后检验)进行统计分析。与CON相比,ECC1和ECC2的峰值扭矩和总功增加,扭矩下降减少。反复进行离心收缩回合产生的扭矩和功结果未改变。肌肉损伤标志物在ECC1后最高(48小时酸痛,72小时肌酸激酶;p<0.05)。与ECC1后相比,ECC2后其总体反应(曲线下面积)消失(p<0.05)。白细胞介素-6在ECC1后高于CON,在ECC2后减弱(p>0.05)。白细胞介素-10和肿瘤坏死因子-α未检测到。所有标志物均显示出较高的个体间变异性。该方案在锻炼大肌肉群后诱导肌肉损伤指标是可行的,但初步结果表明无症状成年人中全身炎症反应较弱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0b4/8934203/a613e4f368af/10-1055-a-1757-6724-i09-2021-0200-0001.jpg

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