Suárez González Luis Ángel, Lozano Martínez-Luengas Iñigo, Montoya Calzada Natalia, Fernández-Samos Gutiérrez Rafael, Vallina-Victorero Vázquez Manuel Javier
University of Leon, Spain; Department of Vascular and Endovascular Surgery, Complejo Asistencial Universitario de León, León, Spain.
Department of Cardiology, Hospital Universitario de Cabueñes, Gijón, Spain.
Asian J Surg. 2023 Jan;46(1):187-191. doi: 10.1016/j.asjsur.2022.03.022. Epub 2022 Mar 19.
Type 2 endoleaks (T2E) continue to be the "Achilles Heel" of endovascular aneurysm repair (EVAR). The aim of this study is to analyze preoperative factors of patients who underwent EVAR to define risk factors for T2E.
From January 2015 to June 2020, 140 of 191 patients who underwent EVAR in our institution meet inclusion criteria for this study. Postoperative image control were performed using duplex ultrasound or CT scan. All T2E detected during follow-up were confirmed by angio CT. Preoperative anatomic and clinical variables were analyzed for T2E using t-test, Mann-Whitney U test and Fisher exact test. ROC curves and the corresponding area under the curve (AUC) were used to describe the predictive accuracy for endoleak.
T2E was detected in 16 patients (11.43%)0.12 of them (75%) were persistent and 10 (62.5%) provoked sac enlargement. Predictive factors for T2E were a greater IMA diameter (2.5 ± 0.5 vs. 3.3 ± 0.5, p < 0.001) and an increasing number of LA (4.8 ± 1.6 vs. 6.7 ± 1.4, p < 0.001). ROC curve analysis stablished thresholds of 3.5 mm for IMA diameter (sensitivity 77%, specificity 86%) and 5.5 for patent LA (sensitivity 88%, specificity 59%) as risk factor to develop T2E.
Preoperative aortic side branches embolization to avoid T2E is not still standarised. We tried to define a group of high-risk patients for T2E. According to our findings, patients with a preoperative IMA> 3 mm and more than 5 patent LA should be considered for pre-EVAR embolization.
2型内漏(T2E)仍然是血管内动脉瘤修复术(EVAR)的“阿喀琉斯之踵”。本研究旨在分析接受EVAR治疗的患者的术前因素,以确定T2E的危险因素。
2015年1月至2020年6月,在本机构接受EVAR治疗的191例患者中有140例符合本研究的纳入标准。术后采用双功超声或CT扫描进行影像检查。随访期间检测到的所有T2E均经血管造影CT证实。采用t检验、Mann-Whitney U检验和Fisher精确检验分析T2E的术前解剖学和临床变量。采用ROC曲线及其相应的曲线下面积(AUC)来描述内漏的预测准确性。
16例患者(11.43%)检测到T2E,其中12例(75%)为持续性内漏,10例(62.5%)导致瘤体增大。T2E的预测因素为肠系膜下动脉(IMA)直径较大(2.5±0.5 vs. 3.3±0.5,p<0.001)和通畅的腰动脉(LA)数量增加(4.8±1.6 vs. 6.7±1.4,p<0.001)。ROC曲线分析确定IMA直径3.5 mm(敏感性77%,特异性86%)和通畅LA数量5.5条(敏感性88%,特异性59%)为发生T2E的危险因素阈值。
术前主动脉侧支栓塞以避免T2E尚未标准化。我们试图确定一组T2E的高危患者。根据我们的研究结果,术前IMA>3 mm且有5条以上通畅LA的患者应考虑在EVAR术前进行栓塞。