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[Measurement of exhaled nitric oxide fraction in lung diseases].

作者信息

Miranda Luz, Guerrero Julia

机构信息

Laboratorio de Inmunomodulación Neuroendocrina, Facultad de Medicina, Universidad de Chile, Santiago, Chile.

出版信息

Rev Med Chil. 2021 Aug;149(8):1173-1181. doi: 10.4067/s0034-98872021000801173.

Abstract

Exhaled Nitric Oxide fraction measurement is a new method for the evaluation of respiratory diseases. It has good correlation with airway inflammation and decreases with the administration of corticosteroids. It is useful as a complement for the diagnosis of asthma, Chronic Obstructive Pulmonary Disease, Cystic Fibrosis and Primary Ciliary Dyskinesia among other respiratory diseases that generate inflammation in the airway. Its assessment is easy, non-invasive, and safe, and the result is obtained immediately. It can be used routinely to evaluate the response and adherence to treatments. This article reviews the biology of Nitric Oxide, and the measurement, interpretation, and main clinical uses of Exhaled Nitric Oxide Fraction.

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