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是否进行包裹?抗反流手术在需要胃造瘘管的婴儿中的应用价值

To Wrap or Not? Utility of Anti-reflux Procedure in Infants Needing Gastrostomy Tubes.

作者信息

Khan Faraz A, Nestor Kelsey, Hashmi Asra, Islam Saleem

机构信息

Division of Pediatric Surgery, Department of Surgery, Loma Linda University, Loma Linda, CA, United States.

Division of Pediatric Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, FL, United States.

出版信息

Front Pediatr. 2022 Mar 7;10:855156. doi: 10.3389/fped.2022.855156. eCollection 2022.

Abstract

PURPOSE

Gastrostomy tube (GT) insertion is commonly performed in children with failure to thrive. Pediatric patients' frequently have gastroesophageal reflux (GER) and discerning pathological GER can be challenging. Moreover, there is some evidence that GT insertion may lead to worsening GER and to avoid a subsequent anti-reflux procedure (ARP), though controversial some surgeons advocate considering an ARP concomitantly. The purpose of this report is to assess outcomes in infants who underwent a GT vs. GT with ARP.

METHODS

Retrospective review of all infants who had a GT placed at a single institution from 2009-2014. The patients were then divided into two cohorts based on the index operation i.e., GT vs GT with ARP and outcomes compared.

RESULTS

226 operations (104 GT, 122 GT with ARP) were performed. The cohorts were similar in gender, gestational age, race, weight, median age, LOS, and proportion of neurologically impaired patients. Preoperative GER was significantly higher in the GT with ARP cohort (91 vs. 18%). No difference in the rate of immediate complications was noted between the two groups. Postoperative increase in anti-reflux medications was significantly higher in the GT cohort ( = 0.01). Post-op GER needing a secondary procedure (ARP or GJ tube) was noted in 21/104 (20%) patients. Those needing an additional procedure vs. those with GT alone were similar in the proportion of patients with pre-op GER, neurologic impairment, type of feeds, and age.

CONCLUSION

Identifying patients who would benefit from a concomitant ARP remains challenging. A fifth of GT patients needed a subsequent procedure despite most high-risk patients having already undergone an ARP. Since the overall rate of complications remained similar, initial GT approach can be considered reasonable.

摘要

目的

胃造口管(GT)置入术常用于发育不良的儿童。儿科患者常伴有胃食管反流(GER),鉴别病理性GER可能具有挑战性。此外,有证据表明GT置入可能导致GER恶化,为避免后续的抗反流手术(ARP),尽管存在争议,但一些外科医生主张同时考虑进行ARP。本报告的目的是评估接受GT与GT联合ARP治疗的婴儿的结局。

方法

对2009年至2014年在单一机构接受GT置入的所有婴儿进行回顾性研究。然后根据初次手术将患者分为两组,即GT组与GT联合ARP组,并比较结局。

结果

共进行了226例手术(104例GT,122例GT联合ARP)。两组在性别、胎龄、种族、体重、中位年龄、住院时间和神经功能受损患者比例方面相似。GT联合ARP组术前GER显著更高(91%对18%)。两组间即刻并发症发生率无差异。GT组术后抗反流药物增加显著更高(P = 0.01)。104例(20%)患者术后出现需要二次手术(ARP或胃空肠造瘘管)的GER。需要额外手术的患者与单纯GT患者在术前GER、神经功能障碍、喂养类型和年龄的患者比例方面相似。

结论

确定哪些患者将从同时进行的ARP中获益仍然具有挑战性。尽管大多数高危患者已经接受了ARP,但五分之一的GT患者仍需要后续手术。由于总体并发症发生率保持相似,初始GT方法可被认为是合理的。

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