Qiu Fanji, Li Jinfeng, Legerlotz Kirsten
Institute of Sport Sciences, Humboldt-Universität zu Berlin, Unter den Linden 6, 10099 Berlin, Germany.
Department of Kinesiology, Iowa State University, Ames, IA 50011, USA.
J Clin Med. 2022 Mar 17;11(6):1666. doi: 10.3390/jcm11061666.
A systematic review and meta-analysis of randomized controlled trials was performed to evaluate the effects of dietary supplements in addition to physiotherapeutic treatment on pain and functional outcomes. PubMed, The Cochrane Library, Web of Science, and Embase were searched from inception to November 2021 (Prospero registration: CRD42021291951). Studies were eligible if the interventions consisted of physiotherapeutic approaches that were combined with dietary supplementation and if they reported measures of pain and/or function. Six studies were included in the meta-analysis. Standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated and analysed using a Review Manager software. Subgroup analysis was performed to explore possible associations between the study characteristics and the effectiveness of the intervention. Additional dietary supplementation during physiotherapeutic treatment significantly improved the reduction in pain score (SMD = −0.74, 95% CI, −1.37 to −0.10; p < 0.05), while it had no effect on functional outcomes (SMD = 0.29, 95% CI, 0.00 to 0.58; p > 0.05). This systematic review and meta-analysis suggests that additional nutritional interventions may improve physiotherapeutic treatment outcomes in the management of tendinopathies.
进行了一项随机对照试验的系统评价和荟萃分析，以评估除物理治疗外，膳食补充剂对疼痛和功能结局的影响。检索了PubMed、Cochrane图书馆、科学网和Embase，检索时间从建库至2021年11月（国际前瞻性系统评价注册库注册号：CRD42021291951）。纳入标准为干预措施包括物理治疗方法与膳食补充剂联合使用，且报告了疼痛和/或功能测量指标的研究。六项研究纳入荟萃分析。使用Review Manager软件计算并分析标准化均数差（SMD）和95%置信区间（CI）。进行亚组分析以探索研究特征与干预效果之间可能存在的关联。物理治疗期间额外补充膳食显著改善了疼痛评分的降低情况（SMD = -0.74，95% CI，-1.37至-0.10；p < 0.05），而对功能结局无影响（SMD = 0.29，95% CI，0.00至0.58；p > 0.05）。这项系统评价和荟萃分析表明，额外的营养干预可能会改善肌腱病管理中物理治疗的效果。
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